Structure of PDB 5yi2 Chain M Binding Site BS01

Receptor Information
>5yi2 Chain M (length=146) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMSLANQIDQFLGTIMQFAENKHEILLGKCESDVKLTSTQEHILMLLAEQ
ISTNAKIAEKLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEK
AVPVAKEHATHHEKTLSTYQELGNKFTDEEQEVISKFLSALTEEFQ
Ligand information
Receptor-Ligand Complex Structure
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PDB5yi2 Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
N21 H23 T37 T39 I63 S64 A66 A67
Binding residue
(residue number reindexed from 1)
N21 H23 T37 T39 I63 S64 A66 A67
Binding affinityPDBbind-CN: Kd=72nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5yi2, PDBe:5yi2, PDBj:5yi2
PDBsum5yi2
PubMed29229866
UniProtQ9CDU5

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