Structure of PDB 5vsw Chain M Binding Site BS01

Receptor Information
>5vsw Chain M (length=140) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSILAIAGVEPYQEKPGEEYMNEAQLAHFRRILEAWRNQLRDEVDRTVTH
MQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDF
GYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5vsw Chain M Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vsw Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.
Resolution4.295 Å
Binding residue
(original residue number in PDB)		C114 C138
Binding residue
(residue number reindexed from 1)		C103 C127
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006302 double-strand break repair
GO:0010468 regulation of gene expression
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vsw, PDBe:5vsw, PDBj:5vsw
PDBsum5vsw
PubMed29478808
UniProtP0ABS1|DKSA_ECOLI RNA polymerase-binding transcription factor DksA (Gene Name=dksA)

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