Structure of PDB 5ms0 Chain M Binding Site BS01

Receptor Information
>5ms0 Chain M (length=425) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEIDVRVQID
RKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESV
TFDRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNI
SLDLGNNAEAVILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRS
KPEMLIELFRIEVPEIGEEVIEIKAAARDPGSRAKIAVKTNDKRIDPVGA
CVGMRGARVQAVSTELGGERIDIVLWDDNPAQFVINAMAPADVASIVVDE
DKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQAKHQA
EAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDE
PTVEALRERAKNALATIAQAQQESL
Ligand information
>5ms0 Chain R (length=29) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucuuuaaaaauaagcccugaagaagggc
..............<<<<<.....>>>>>
Receptor-Ligand Complex Structure
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PDB5ms0 Structural basis for lambda N-dependent processive transcription antitermination.
Resolution9.8 Å
Binding residue
(original residue number in PDB)		S232 G249 G256 A315
Binding residue
(residue number reindexed from 1)		S232 G249 G256 A315
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0001000 bacterial-type RNA polymerase core enzyme binding
GO:0003676 nucleic acid binding
GO:0003700 DNA-binding transcription factor activity
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0031554 regulation of termination of DNA-templated transcription
GO:0031564 transcription antitermination
GO:0032784 regulation of DNA-templated transcription elongation
GO:0042254 ribosome biogenesis
GO:0051259 protein complex oligomerization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008023 transcription elongation factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ms0, PDBe:5ms0, PDBj:5ms0
PDBsum5ms0
PubMed28452979
UniProtP0AFF6|NUSA_ECOLI Transcription termination/antitermination protein NusA (Gene Name=nusA)

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