Structure of PDB 5iro Chain M Binding Site BS01

Receptor Information
>5iro Chain M (length=265) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHLRC
WALSFYPAEITLTWQEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQR
YTCHVQHEGLPKPLT
Ligand information
>5iro Chain N (length=9) Species: 11908 (Human T-cell leukemia virus type I) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLFGYPVYV
Receptor-Ligand Complex Structure
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PDB5iro Structure of the Adenovirus Type 4 (Species E) E3-19K/HLA-A2 Complex Reveals Species-Specific Features in MHC Class I Recognition.
Resolution2.64 Å
Binding residue
(original residue number in PDB)
Y7 Y59 E63 K66 H70 T73 V76 D77 T80 L81 Y99 T143 K146 W147 Q155 L156 Y159 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y59 E63 K66 H70 T73 V76 D77 T80 L81 Y99 T143 K146 W147 Q155 L156 Y159 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5iro, PDBe:5iro, PDBj:5iro
PDBsum5iro
PubMed27385781
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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