Structure of PDB 5e6i Chain M Binding Site BS01

Receptor Information
>5e6i Chain M (length=268) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPW
IEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGC
DVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAH
VAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDEATLR
CWALSFYPAEITLTWQRDGEDTQDTELVETRPAGTFQKWAAVVVPSGQEQ
RYTCHVQHEGLPKPLTLR
Ligand information
>5e6i Chain O (length=9) Species: 947055 (Influenza A virus (A/Boston/2747243M/2009(H1N1))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GILGFVFTL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5e6i Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2
Resolution4.0 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 T73 D77 W147 V152 L156 Y159 W167
Binding residue
(residue number reindexed from 1)
Y6 E62 K65 T72 D76 W146 V151 L155 Y158 W166
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5e6i, PDBe:5e6i, PDBj:5e6i
PDBsum5e6i
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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