Structure of PDB 4v1o Chain M Binding Site BS01

Receptor Information
>4v1o Chain M (length=299) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDH
NGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVKDN
EVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAA
SILIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNIAQNLTYIPRFC
SHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPI
TAAKVGQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGV
Ligand information
>4v1o Chain N (length=50) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacagtagcacgctgtgtatataatagtgtgttgtacagcacaactgcgc
Receptor-Ligand Complex Structure
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PDB4v1o Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Resolution9.7 Å
Binding residue
(original residue number in PDB)		K201 Y313 K314 G341 V342
Binding residue
(residue number reindexed from 1)		K177 Y270 K271 G298 V299
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000993 RNA polymerase II complex binding
GO:0001139 RNA polymerase II complex recruiting activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001113 transcription open complex formation at RNA polymerase II promoter
GO:0001174 transcriptional start site selection at RNA polymerase II promoter
GO:0006352 DNA-templated transcription initiation
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0010467 gene expression
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0070897 transcription preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0097550 transcription preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v1o, PDBe:4v1o, PDBj:4v1o
PDBsum4v1o
PubMed25652824
UniProtP29055|TF2B_YEAST Transcription initiation factor IIB (Gene Name=SUA7)

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