Structure of PDB 4u7u Chain M Binding Site BS01

Receptor Information
>4u7u Chain M (length=489) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALAL
LVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPF
MQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFN
QANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFP
NESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKC
SCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAF
TTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGY
RNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFA
EGFGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQ
LCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKP
Ligand information
>4u7u Chain X (length=61) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaaccgggcucccugucgguuguaauugauaauguugagaguuccccg
cgccagcgggg
.............................................<<<<<
<....>>>>>>
Receptor-Ligand Complex Structure
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PDB4u7u Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
Resolution3.003 Å
Binding residue
(original residue number in PDB)
F129 V130
Binding residue
(residue number reindexed from 1)
F129 V130
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4u7u, PDBe:4u7u, PDBj:4u7u
PDBsum4u7u
PubMed25118175
UniProtQ46901|CSE1_ECOLI CRISPR system Cascade subunit CasA (Gene Name=casA)

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