Structure of PDB 4en2 Chain M Binding Site BS01

Receptor Information
>4en2 Chain M (length=256) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGM
PELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIP
PDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTA
NNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMR
AHFGLKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGD
YQLRTQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4en2 Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef.
Resolution2.58 Å
Binding residue
(original residue number in PDB)		F172 D174 R201 T223 R225 Y384 R393 Y394 L395 K396 P407 W408 V409 R410
Binding residue
(residue number reindexed from 1)		F15 D17 R44 T66 R68 Y217 R226 Y227 L228 K229 P240 W241 V242 R243
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4en2, PDBe:4en2, PDBj:4en2
PDBsum4en2
PubMed22705789
UniProtP35585|AP1M1_MOUSE AP-1 complex subunit mu-1 (Gene Name=Ap1m1)

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