Structure of PDB 4emz Chain M Binding Site BS01

Receptor Information
>4emz Chain M (length=255) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMP
ELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPP
DGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTAN
NVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRA
HFGLKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDY
QLRTQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4emz Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		F172 D174 R225 Y384 R393 Y394 L395 K396 P407 W408 V409 R410 I412
Binding residue
(residue number reindexed from 1)		F14 D16 R67 Y216 R225 Y226 L227 K228 P239 W240 V241 R242 I244
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4emz, PDBe:4emz, PDBj:4emz
PDBsum4emz
PubMed22705789
UniProtP35585|AP1M1_MOUSE AP-1 complex subunit mu-1 (Gene Name=Ap1m1)

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