Structure of PDB 2z5t Chain M Binding Site BS01
Receptor Information
>2z5t Chain M (length=89) Species:
7955
(Danio rerio) [
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PGEGTQVHPRAPLLQILKVAGAQEEVFTVKEVMHYLGQYIMMKQLYDKQR
QHIVHCHDDPLGELLEVGSFSVKNPSPLYEMLKRNLVIL
Ligand information
>2z5t Chain P (length=11) Species:
9606
(Homo sapiens) [
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ETFSDLWKLLP
Receptor-Ligand Complex Structure
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PDB
2z5t
Molecular basis for the inhibition of p53 by Mdmx.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
M50 G54 I57 Y63 Q68 H69 P92 Y96
Binding residue
(residue number reindexed from 1)
M33 G37 I40 Y46 Q51 H52 P75 Y79
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0043066
negative regulation of apoptotic process
GO:0051726
regulation of cell cycle
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:2z5t
,
PDBe:2z5t
,
PDBj:2z5t
PDBsum
2z5t
PubMed
17938582
UniProt
Q7ZUW7
|MDM4_DANRE Protein Mdm4 (Gene Name=mdm4)
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