Structure of PDB 2xa7 Chain M Binding Site BS01

Receptor Information
>2xa7 Chain M (length=428) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNI
ARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEEN
IKNNFVLIYELLDEILDFGYPQNSETGALKTFITQHQTKEEQSQITSQVT
GQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYL
SGMPECKFGMNDKIVIESMEQKLISEEDLGKQSIAIDDCTFHQCVRLSKF
DSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVI
KSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKR
MAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVF
EPKLNYSDHDVIKWVRYIGRSGIYETRC
Ligand information
Receptor-Ligand Complex Structure
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PDB2xa7 A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Resolution3.1 Å
Binding residue
(original residue number in PDB)		F174 D176 V412 K431 W432 V433 R434
Binding residue
(residue number reindexed from 1)		F168 D170 V394 K413 W414 V415 R416
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2xa7, PDBe:2xa7, PDBj:2xa7
PDBsum2xa7
PubMed20603002
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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