Structure of PDB 1xmo Chain M Binding Site BS01

Receptor Information
>1xmo Chain M (length=125) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEA
EVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQ
RTRTNARTRKGPRKTVAGKKKAPRK
Ligand information
>1xmo Chain A (length=1507) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuaggaacccgggugaaagccuggggugc
cccggggagcccuagcacaggugcugcauggccgucgucagcucgugccg
ugagguguuggguuaagucccgcaacgagcgcaacccccgccguuaguug
ccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgggagg
aaggaggggacgacgucuggucagcauggcccuuacggccugggcgacac
acgugcuacaaugcccacuacaaagcgaugccacccggcaacggggagcu
aaucgcaaaaaggugggcccaguucggauuggggucugcaacccgacccc
augaagccggaaucgcuaguaaucgcggaucagcaugccgcggugaauac
guucccgggccuuguacacaccgcccgucacgccaugggagcgggcucua
cccgaagucgccgggagccuacgggcaggcgccgaggguagggcccguga
cuggggcgaagucguaacaagguagcuguaccggaaggugcggcuggauc
acuuucu
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>.....
.<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<...
...>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<
<<.....>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<
.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>>>>
>........<<<....<<<<....>>>>..>>>..>>.>>>>>>......
...............................<<<<<........<<....
....>>...........>>>>>......<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>........
...<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>
>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<
<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>....
......<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<
<<..>>>...>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.
...>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<..<
<...<<<.....>>>.>>...>>>>>>>.....<<<<<....>>>>>...
.....>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>
>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>.
...>>>.....>>>>>>>......<..<.<<<<<<<........>>>>>>
>>...>.....>>>>>>....<<<<<<<.........>>>>>>>......
>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<
<<<...<.<<<<....<<<<..>>>>.>>>>.>..>>>>>>>>>>>>>..
>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>.....
.......
Receptor-Ligand Complex Structure
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PDB1xmo The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Resolution3.25 Å
Binding residue
(original residue number in PDB)		K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 N77 I78 R88 R91 H92 L96 P97 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 K120 A123 R125 K126
Binding residue
(residue number reindexed from 1)		K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 N76 I77 R87 R90 H91 L95 P96 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 K119 A122 R124 K125
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1xmo, PDBe:1xmo, PDBj:1xmo
PDBsum1xmo
PubMed15558052
UniProtP80377|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)

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