Structure of PDB 1pzu Chain M Binding Site BS01

Receptor Information
>1pzu Chain M (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGY
MENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKV
LEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRV
HIPESSGRIVSLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRT
PVKVNFYVINGKRKRSQPQHFTYHPV
Ligand information
Receptor-Ligand Complex Structure
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PDB1pzu An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R421 S429 R430 R537 Q571
Binding residue
(residue number reindexed from 1)		R23 S31 R32 R139 Q173
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1pzu, PDBe:1pzu, PDBj:1pzu
PDBsum1pzu
PubMed12949491
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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