Structure of PDB 9fpz Chain Lr Binding Site BS01

Receptor Information
>9fpz Chain Lr (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGV
EPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNK
YRPDLRMAAIRRASAILRSQKPVMV
Ligand information
>9fpz Chain 1 (length=300) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaguccuucugaucgaggcccagcccguggacggugugaggccgguagu
ugaaaagaacuuugaagagagaguucaagagggcgccgcccggaggauuc
aacccggcggcggguccggccgugucggcggcccggcggaucuuucccgc
gcgggggaccgucccccgaccggcgaccggccgccgccgggcgcauuucc
accgcggcgguucaaacgagaacuuugaaucggguucagauccccgaauc
uuggaaagcgucgcgguuccggcggcguaagggcugguagcagccgacuu
<....<<<<......>>>>.....((......<<<.....))>>>...>.
.........<<<<....>>>>..............<<<<<<<<.<<<...
..<<<<<<<<<<<..<<<<<<<..<....<.....<<<<.<<<..<<<..
..>>>>>>>>>>.>...>..>>>>...>>>>>>>>>>>>>>......>>>
.>>>.>>>>><<<<<<.......>>>>>><<<<<........>>>>>...
.......<<<<<<<.......>>>>>>><<<<<<<<....>>>>>..>>>
Receptor-Ligand Complex Structure
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PDB9fpz Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome
Resolution2.69 Å
Binding residue
(original residue number in PDB)
R46 R66 R67 S68 K84 N85 R87 S92 H95 M96 K99 N100
Binding residue
(residue number reindexed from 1)
R45 R65 R66 S67 K83 N84 R86 S91 H94 M95 K98 N99
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0030425 dendrite
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0044297 cell body
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:9fpz, PDBe:9fpz, PDBj:9fpz
PDBsum9fpz
PubMed
UniProtP46779|RL28_HUMAN Large ribosomal subunit protein eL28 (Gene Name=RPL28)

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