Structure of PDB 7zjx Chain Lr Binding Site BS01

Receptor Information
>7zjx Chain Lr (length=91) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRA
VGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ
Ligand information
>7zjx Chain L5 (length=3732) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcgguggggcgcgggaaau
guggcguacggaagacccacuccccggcgccgcucguggggggcccaagu
ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc
ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca
gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac
cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga
gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg
caguccgcccggaggauucaacccggcggcgugguccggccgugccggcg
gucucggcggaucuuucccgcuccggggucggcgggggaccgccccccgg
ccggcgaccggccgccgccgggcgcauuuccaccgcggcggugcgccgcg
accggcuccgggacggcugggaaggccccggcggggaagguggcccgggg
ggacgccucgccggcgggcgcgaccccuccccggguguuacagccccgcc
ccggcagcagcagcucgccgaaucccggggccgagggagcgagaccugug
ucgccgcgcucuccccccucgggggggccgggccgccccucccacggcgc
gaccgcucggggcggacuguccccagugcgccccgggcgugucacgccgu
cgggcucgggggaggccacggcgcgucgcgcgccggcgcgcgcgcgcgag
cgagcgcacggggucggcggcgaugucggcuacccacccgacccgucuug
aaacacggaccaaggagucuaacacgugcgcgagucgggggcucgcacga
aagccgccguggcgcaaugaaggugaaggccggcggcggcgccgucgucg
gccgaggugggaucccgaggcccuuccaguccgccgagggcgcaccaccg
gcccgucucgcccgccgcgccggggagguggagcacgagcgcacguguua
ggacccgaaagauggugaacuaugccugggcagggcgaagccagaggaaa
cucugguggagguccguagcgguccugacgugcaaaucggucguccgacc
uggguauaggggcgaaagacuaaucgaaccaucuaguagcugguucccuc
cgaaguuucccucaggauagcuggcgcucucgcaaccccgcaguuuuauc
cgguaaagcgaaugauuagaggucuuggggccgaaacgaucucaaccuau
ucucaaacuuuaaauggguaagaagcccggcucgcuggcguggagccggg
cguggaaugcgagugccuagugggccacuuuugguaagcagaacuggcgc
ugcgggaugaaccgaacgccggguuaaggcgcccgaugccgacgcucauc
agaccccagaaaagguguugguugauauagacagcaggacgguggccaug
gaagucggaauccgcuaaggaguguguaacaacucaccugccgaaucaac
uagcccugaaaauggauggcgcuggagcgucgggcccauacccggccguc
gcuggcagucggcagagcgagaaagagaguggagccgcggacgcuacgcc
gcgacgaguaggagggccgcugcggugagccuugaagccuagggcgcggg
cccggguggagccgccgcaggugcagaucuuggugguaguagcaaauauu
caaacgagaacuuugaaggccgaaguggagaaggguuccaugugaacagc
aguugaacaugggucagucgguccugagagaugggcgagcgccguuccga
agggacgggcgauggccuccguugcccucagccgaucgaaagggagucgg
guucagauccccgaauccggaguggcggagaugggcgccgcgaggcgucc
agugcgguaacgcgaccgaucccggagaagccggcgggagccccggggag
aguucucuuuucuuugugaagggcagggcgcccuggaauggguucgcccc
gagagaggggcccgugccuuggaaagcgucgcgguuccggcggcguccgg
ugagcucucgcuggcccuugaaaauccgggggagaggguguaaaucucgc
gccgggccguacccauauccgcagcaggucuccaaggugaacagccucug
gcauguuggaacaauguagguaagggaagucggcaagccggauccguaac
uucgggauaaggauuggcucuaagggcugguagcagccgacuuagaacug
gugcggaccaggggaauccgacuguuuaauuaaaacaaagcaucgcgaag
gcccgcggcggguguugacgcgaugugauuucugcccagugcucugaaug
ucaaagugaagaaauucaaugaagcgcggguaaacggcgggaguaacuau
gacucucuuaagguagccaaaugccucgucaucuaauuagugacgcgcau
gaauggaugaacgagauucccacugucccuaccuacuauccagcgaaacc
acagccaagggaacgggcuuggcggaaucagcggggaaagaagacccugu
ugagcuugacucuagucuggcacggugaagagacaugagagguguagaau
aagugggaggcccgggccgccggugaaauaccacuacucuuaucguuuuu
ucacugacccggugaggcgggggggcgagccccgaggggcucucgcuucu
ggcgccaagcgccgggccccgucgguccgggccggcggcggccgggcgcg
acccgcuccggggacagugccagguggggaguuugacuggggcgguacac
cugucaaacgguaacgcagguguccuaaggcgagcucagggaggacagaa
accucccguggagcagaagggcaaaagcucgcuugaucuugauuuucagu
acgaauacagaccgugaaagcggggccucacgauccuucugagcuuuugg
guuuuaagcaggaggugucagaaaaguuaccacagggauaacuggcuugu
ggcggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggc
ucuuccuaucauugugaagcagaauucaccaagcguuggauuguucaccc
acuaauagggaacgugagcuggguuuagaccgucgugagacagguuaguu
uuacccuacugaugauguguuguugccaugguaauccugcucaguacgag
aggaaccgcagguucagacauuugguguaugugcuuggcugaggagccaa
uggggcgaagcuaccaucugugggauuaugacugaacgccucuaagucag
aaucccgcccaggcggaacgauacggcagcgccgaaggagccucgguugg
ccucggauagccggucccccgcgggguccggugcggagagcccuucgucc
cgggaaauggggcgcggccggaaagggggccgcccucucgcccgucacgc
accgcacguucguggggaaccuggcgcuaaaccauucguagacgaccugc
uucugggucgggguuucguacguagcagagcagcucccucgcugcgaucu
auugaaagucagcccucgacacaaggguuugu
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..<<<..<<<<<...<<<<<<<<<<.....>>>>>>.>>>>...
..>>>>>..<<<<<<<<<....<<<<<<<<.<<<....<<<<<<<<....
<<<<......>>>>.....((......<<<.....))>>>...>.>>>>>
>>>>>>>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>
>>>>.....<<<<<..((((((>>>>>..>>>..................
................<<....>>...............<<<<....>>>
>..................................<<<<<<<<..<<<.<
<...<<<<<<<<.<<<.....<<<<<<<<<<....<<<<<<<.<<<<<.<
.....<<<<<.<<<..<<<<.<.........>>>>>>>>>>>>>.>>>>>
>>>>>...>>>.>>>>>>>>>>......>>>.>>>.>>>>>...<<<<<<
<.<<<<<<<<<<.<<<<...<<..<<<..<<<<<<<......<<<<.<<<
<<.......<....>...........>>.>>>>>>>.......>>>>>>>
..>>>.........>>>>>>...>>>>>>>>>>.....<<.....[[>>.
.....<<<<<..<<<<<<<.>>>>>>>...<<<<.<<<<.<<<<<<<<<.
<<<<<<.....<<<.<<<<....>>>>.>>>.....>>>.>>>.>>>>>>
.>>>...>>>>..>>>>...<<<....<<..........>>...>>>...
..>>>>>......>>.>>>>>...>>>>>...>>>>>>>>..<<<<....
....>>>><<<<<<...<<<<<<<<<<<<<<..<<<...<<<<.......
.>>>>.....>>>...<<....>>...<<<<<<<<<.<<..>>.>>>>>>
>>>..<<<<<...<<<..<<....{{...{{..>>..>>>....>>>>>.
<<<<<<<<<.<<<<......>>>>>>>>>>>.>>....>>>>>>>>>>>>
>>.<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....
>>>>>>>.....>>>...<<<..<<.<<........>>>>.>>>....>>
>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<<<<<
<....<.<<<....>>>.><<.<<<<<<<..........<<<.<<<<<<<
<<...<<<....<<<..<.<<<..<<<<<<.<.....>.>>>>>>>>>.>
..>>>..>>.>...>>>>>>>...<<<<<<<<<.........>>>>>>>>
>....>>>>>>>>>>>>..>>..<<<<.<<<<<.....>>>>>.>>>>..
..<<<......>>>...<<<<<<<...<<<(((.......<<<<<.....
<<..........<<<.<<<<<<<<<<.......<<<<<..<....<<...
......>>....>..........<<......>>...>>>>>...>>>>>>
>>>>>>>..........))).>>...>>>>>..>>>...>>>>>>><<<<
<<.<<<.......]]...........}}...}}..............>>>
>>>>>>....>>>>>>...<<<<<<<<.<<......<<<<.<<<<....>
>>>>>>>...>>>>>>>>>>........>>>>>><<.....<<.....<<
<<<<.......>>>>>>.<<<.....<<<<<.<<...<<<<<<...<<..
...>>.>>>>>>....((<<<<<<...<<....<<<....>>>.......
...<<.<<<<<<<<<...>>>>>>>>>>>......>>....>>>..<<<<
<........>>>>>))<<<<....<<<<<..<<<<<<<<....>>>>>>>
>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<<<.<<<<<<<<
<<..[[[..>>>>>>....<<<<<.<<<<.<<<<.....<<<.....>>>
.....>>>>>>>>..>>>>>.....<<<<<<<.......>>>>>>>>>>>
...>>>>>>>>>>>>.........>>>>>>>..>..........>>.>>>
.>>>>.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>
>>....<<<<.....<<<<<<<.<<...............<<<<<....<
....>.....>>>>><<.<<<<<<<<<<<....>>>>>..>>>>>>.>>.
...........<<<<<<<<<..<<<.........>>>..<<<<<<<....
<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<....<<
<.....<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<......
.>>>>>>........<...........<<<<<.......>>>>>.....>
.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>....>>
....<<<<<........>>>>>....<<<<<..<<<.<<......<<<<.
<<<<<<..<<<<..<<<<<<<<<.<<<<<<.<<<<<<<<<..........
.<<<<<..<<<<..>>>>............>>>>>..>>>>>>.>>>.>>
>>>>...<<<<<.....<<<<.....<<<<<<....>>>>>>........
........<<<<<..<<...<<...<<..>>...>>....>>..>>>>>.
.>>>>..>>>>>....>>>>>>>>>...>>>>...<<<.....>>>..<<
<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<......
.>>>>>>.....<<.[.(((>>....>>>>>>>...<<<..<<<<.....
..>>>>..>>><<<<....>>>>>>)))].....<<<<<<<..<<<..))
)))).>>>>>>>>>>.........>>>>..>>>>>>.......<<.<...
<<<<<<...<<.......>>...>>>>>>....>.>.>.......<<<<<
.<<<<<<..<.<.<<<<<......>>>>>...>.>.<<<.........>>
>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....
>>..>>>.>>>>>.....<<<<<<.<..<<<..<.<<<<<..........
.......>>>>>.><<<<....<<<<....<<.<<<<<<<]]].>>>>>.
.>>.>>...>>>>...>>>><<<<<...<<<<<...........>>>>>.
..>>>>>.>>>...>.>>>>>>.....<<<<<<<..<<..<<<<....<<
<........<<<<<..<<<<..>>>>.>>>>>.......>>>...<<<..
<<<<....<<<<.<<<<<..........>>>>>>>>>...>>>>..>>>.
.............>>>>..>>>>>>>>><<<<<.................
...<<.<<<<<<<.<<.....<<<<.<..<<<<<......>>>>>..>>>
>>....>>....>>>>.>>>.>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zjx Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
A2 K3 R4 T5 K6 K7 V8 G9 I10 K13 Y14 G15 T16 R17 Y18 G19 A20 S21 R23 H34 F41 C42 K44 K46 K48 R49 R50 A51 G58 S59 M61 K62 W69
Binding residue
(residue number reindexed from 1)
A1 K2 R3 T4 K5 K6 V7 G8 I9 K12 Y13 G14 T15 R16 Y17 G18 A19 S20 R22 H33 F40 C41 K43 K45 K47 R48 R49 A50 G57 S58 M60 K61 W68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7zjx, PDBe:7zjx, PDBj:7zjx
PDBsum7zjx
PubMed35709277
UniProtA0A6I9ZMF9

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