Structure of PDB 8pv8 Chain Lq Binding Site BS01

Receptor Information
>8pv8 Chain Lq (length=139) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNVSADLIWEVSRNYNSFLVKQRTGTFSRDALNLTNQHSRKHAGFVNDKA
LGIVPAEKGVKVIAKKVKAANKPASSLYTVTYKSTARKAYKAIASQAAKH
GYRADLRQAAVARASAILRSQRPVKPEPPKKLRGAAARR
Ligand information
>8pv8 Chain C1 (length=3085) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacuau
gcuuggauagggugaagccagaggaaacucugguggaggcucgcagcggu
ucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacuaa
ucgaaccaucuaguagcugguuaccgccgaaguuuccggauagcaguguc
gaccuucaguuuuaugagagcgaaugauuagggacucgggggcgccuuca
uccauucucuguaagaagcccuuguuacuuaacugaacgugggcgaaugu
cgacacuagugggccauuuuugguaagcagaacuggcgaugcgggaugaa
ccgaacgcgggguuaaggugccggaguggacgcucaucagacaccacaaa
aggcguuaguacaucuugacagcaggacgguggccauggaagucggaauc
cgcuaaggacuguguaacaacucaccugccgaauguacuagcccugaaaa
uggauggcgcucaagcgucccacccauaccccgcccucaggguagaaacg
augcccugaggaguaggcggccguggaggucagugacgaagccuagggcg
ugagcccgggucgaacggccucuagugcagaucuuggugguaguagcaaa
uacuucaaugagaacuugaaggaccgaaguggggaaagguuccaugugaa
cagcgguuggacauggguuagucgauccuaagccauagggaaguuccguu
ucaaaggggcacucgugccccguguggcgaaagggaagccgguuaauauu
ccggcaccuggauguggguuuugcgcggcaacgcaacugaacgcggagac
gacggcgggggccccgggcagaguucucuuuucuucuuaacggucuauca
cccuggaaacaguuugucuggagauaggguuuaauggccggaagagcccg
acacuucugucggguccggugcgcucucgacgucccuugaaaauccgcgg
gagggaauaauucucacgccaggucguacucauaaccgcagcaggucccc
aaggugaacagccucugguugauagaacaauguagauaagggaagucggc
aaaauagauccguaacuucgggaaaaggauuggcucuaaggguugguaac
aaccaacuuagaacugguacggacagggggaaucugacugucuaauuaaa
acauagcauugcgauggccagaaagugguguugacgcaaugugauuucgc
ccagugcucuaugucaaagugaagaaauucaaccaagcgcggguaaacgg
cgggaguaacuaugacucucuuaagguuaacgagauucccacugucccua
ucuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaaucag
cggggaaagaagacccuguugagcuugacucuaguuugacauugugaaaa
gacauaggagguguagaauaggugggagcuucggcgccagugaaauacca
cuacuccuauuguuuuuuuacuuauucaaugaagcggggcuggacuugcg
uccaacuucuggaguuaagguccuucgcgggccgacccggguugaagaca
uugucagguggggaguuugggcacaucugcagguguccuaaggggggcuc
auggagaacagaaaucuccaguagaacaaaaggguaaaaguccccuugau
uuugauuuuugugaauacaaaccaugaaaguguggccccuuuagucccuc
gaaauuugaggcuagaggaaguuaccacagggauggcuuguggcggccaa
gcguucauagcgacgucgcuuugauccuucgaugucggcucuuccuauca
uaccgaagcagaauucgguaagcguuggauuguacccacuaauagggaac
gagcuggguuuagaccgucgugagacagguuaguuuuacccuacugauga
acucgucgcaaugguaauucagcuuaguacgagaggaaccgcugauucag
auaauugguuuuugcgguuguccgaccgggcagugccgcgaagcuaccau
cugcuggauaauggcugaacgccucuaagucagaauccaugccagaacgc
gacgauacuacccgcacguuguagacguauaagaauaggcuccggccucg
uauccuagcaggcgauuccuccgccggccucgaaguggccgucgguaauu
cgcguauugcaauuuagacacgcgcgggaucaaauccuuugcagacgacu
uagaugugcgaaaggguccuguaagcaguagaguagccuuguuguuacga
ucugcugaggguaagcccuccuucgccuagauuuc
........................<<<<<<.....<......>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<<...<<<<......>>>>.((..
....<<<.....))>>>.>..>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<..(((((
(>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<........>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<...<<....>>..
.>>>>.>>.>>....>>>>.>>>>>>>>>.<<.<..<<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.
<<.<<........>>>>>>>>....>>>>>>>>>...<<.......>>..
....>>>>>>...>..>.>>...<<<<<......<<..>>..<<<<<<<<
<.....<<.<<<<<<<.........<<....<<<...<<<<<..>>>>>.
>>>..>>..>>>>>...<<<<.<<<<.<......>>>>>.>>>>.>>>>.
>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......
>>>...<<<<<<<...<<<(((.....<<<<<<.....<<..........
<<<.<<<<<<<<<<.......<<<<<.<<<...<<.........>>...>
>>.........<<......>>...>>>>>...>>>>>>>>>>>>>.....
.....))).>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.......
..>>>>>>>>>....>>>>>.<.<<<<<<<<.<<......<<<<.<<<<.
...>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<<....<<...
..<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...
<<.....>>.>>>>>>....((<<<<<<...<<<...<<<....>>>...
.....<<<<<<....>>>>>>....>>>....>>...<<<<<........
>>>>>))<<<<.<<<<.<<<....<<<....>>>...<.((<<<<<<...
<<<<.<<<<<<<.<<<<<.<<<<...[[..>>>>.><...<<<<<....<
<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<<<<
<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>.
..>.....>>>...>>>>>>>>>>>>..>>.....<<......>>>>>>>
.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<.........
......<<<<<....<<..>>.....>>>>><<.<<<<<<<<<<<....>
>>>>..>>>>>>.>>............<<<<<<<<<..<<<.........
>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>......<<
<..<<<<<<..<<<.....<<<<....>>>>.....>>>.>>>>..>>>>
><<<<<<.......>>>>>>..........>>.>>>>>>>.....>>.>>
>>>>>..>>>>>>...>>>....<<<<<........>>>>>....<<<<<
..<<<........<<<<<.<<<<<<..<<<<<.<<<<<<<<..<<<<<<<
<<<<<<<<<<..........<<<<<..<<....>>............>>>
>>.>>>>>>>.>>>>>>>>>>...<<<<<.....<<<<..<<<<<....>
>>>>..........))..<<<<<.....>>>>>..>>>>..>>>>>....
.>>>>>>>>..>>>>>...<<.<<<<<<..>>>>>>>>...<<<<<<<..
.<<<<<<.......>>>>>>.....<<....((>>....>>>>>>>...<
<<.<<<<<....>>>>.>>>>.<<<....>>>...))<<<<<<<..<<<<
.))))))>>>>>>>>>>>.>>>>..>>>>>>>.........<<<<<<...
<<.......>>...>>>>>>...............<<<<...<<<<..<.
<<<<<<<......>>>>>>>...>.<<<.<...>.>>>.....>>>>...
..>>>>......<<<<<<<....>>>.>>>>........>>>.>>>>>..
..<<<<<<<..<<<<.<.<<<<<.................>>>>>.><<<
<<...<<<<....<<<<<<<<<<]]..>>>>>..>>>>>...>>>>..>>
>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>....>>
>>>>>.....<<<<<.<<.<<<......<<.......<<<....>>>...
.>>........<<<<.....<<<.<<<<<.......>>>>>.>>>....>
>>>..............>>>>>.>>>>>...<<<<<<<............
.>>....<<<<<<<<<.<<<....<<<<....<<<<<......>>>>>..
.>>>>...>>>....>>>>..>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv8 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.91 Å
Binding residue
(original residue number in PDB)		W10 R14 Y16 S18 K22 R24 R30 H39 R41 K42 K67 K69 Y79 V81 Y83 K84 R88 K89 A93 S96 Q97 H101 Y103 R104 A105 D106 R108 K132 R134
Binding residue
(residue number reindexed from 1)		W9 R13 Y15 S17 K21 R23 R29 H38 R40 K41 K66 K68 Y78 V80 Y82 K83 R87 K88 A92 S95 Q96 H100 Y102 R103 A104 D105 R107 K131 R133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pv8, PDBe:8pv8, PDBj:8pv8
PDBsum8pv8
PubMed37921038
UniProtG0SHJ6

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