Structure of PDB 8i9z Chain Lq Binding Site BS01

Receptor Information
>8i9z Chain Lq (length=207) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITVAGVRQNVAELLDYSNNVKKRNFLETVELQIGLKNYDPQRDKRFSGTV
KLPTVPRPNMSICILGDQHDIDRAKHGGIDAMSADDLKKLNKNKKLIKKL
ARKYDAFIASESLIKQIPRLLGPGLSKAGKFPTPVSHSDDLSAKVNEVKS
TVKFQLKKVLCMGVAVGNVGMTQEQLVANIMLAINYLVSLLKKGWQNVGS
LTIKATM
Ligand information
>8i9z Chain C1 (length=2787) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuaugcuuggauagggug
aagccagaggaaacucugguggaggcucgcugacgugcaagaucgucaaa
ucugagcaugggggcgaaagacuaaccaucuaguagcugguuaccgccga
aguuucccucaggauagcagugucgaccuucaguuuuaugagguaaagcg
aaugaacuuuaaauauguaagaagcccuuguuacuuaacugaacgugggc
auucgaauguaucgacacuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacgcgggguuaaggugccggaguggacgcucauc
agacaccacaaaaggcguuaguacaucuugacagcaggacgguggccaug
gaagucggaauccgcuaaggacuguguaacaacucaccugccgaauguac
uagcccugaaaauggauggcgcucaagcgucccacccauaccccgcccuc
aggguagaaacgaugcccugaggaguaggcggccguggaggucagugacg
aagccuagggcgugagcccgggucgaacggccucuagugcagaucuuggu
gguaguagcaaauacuucaaugagaacuugaaggaccgaaguggggaaag
guuccaugugaacagcgguuggacauggguuagucgauccuaagccauag
ggaaguuccguuucaaaggggcacucgugccccguguggcgaaagggaag
ccgguuaauauuccggcaccuggauguggguuuugcgcggcaacgcaacu
gaacgcggagacgacggcgggggccccgggcagaguucucuuuucuucuu
aacggucuaucacccuggaaacaguuugucuggagauaggguuuaauggc
cggaagagcccgacacuucugucggguccggugcgcucucgacgucccuu
gaaaauccgcgggagggaauaauucucacgccaggucguacucauaaccg
cagcagguccccaaggugaacagccucugguugauagaacaauguagaua
agggaagucggcuccguaacuucgggaaaagggcucuaaggguugggcac
guugggcuuugggcggacgcccugggagcagagggccucuagccgggcaa
ccggccggcggcccucagcacccgggguugaagcccuuagcccggcgugc
gguuaacaaccaacuuagaacugguacggacacacugucccuaucuacua
ucuagcgaaaccacagccaagggaacgggcuuggcaaaaucagcggggaa
agaagacccuguugagcuugacucuaguuugacauugugaaaagacauag
gagguguagaauaggugggagcuucggcgccagugaaauaccacuacucc
uauuguuuuuuuacuuauucaaugugaagacauugucagguggggaguuc
cuuuagucccucgaaauuugaggcuagaggagaaaaguuaccacagggau
aacuggcuuguggcggccaagcguucauagcgacgucgcugaugucggcu
cuuccuaucauaccgaagcagaauucgguaagcguuggauuguucaccca
cuaauagggagugagcuggaccgucgugagacagguuagucccuacugau
gaacucgucgcaaugguaauucagcuuaguacgagaggaaccgcugauuc
agauaauugguuuuugcgguuguccgaccgggcagugccgcgaagcuacc
aucugcuggauaauggcugaacgccucuaagucagaauccaugccagaac
gcgacgauacuacccgcacguuguagacguauaagaauaggcuccggccu
cguauccuagcaggcgauuccuccgccggccucgaaguggccgucgguaa
uucgcguauugcaauuuagacacgcgcgggaucaaauccuuugcagacga
cuuagaugugcgaaaggguccuguaagcaguagaguagccuuguuguuac
gaucugcugaggguaagcccuccuucgccuagauuuc
........................<<<<<<.....<......>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<....<<<
<<<<<.<<<<..<<<...<<<<.....>>>>...>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<<.
..<<<<<<<....>>>>>>>...>.>>>..<<<<<........>>>>>..
>>>>>>>>>..<<.<....>.>>.>>>>>>>.....>.>>...<<<<<..
..<.<<<....>>>.><<<<<<<<<<....<<.<<<<<<<.....<<<..
......>>.>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<...<<<(((.....<<<<<<.....
.<..........<<<.<<<<<<<<<<.....<.<<<<<.<<<...<<...
......>>...>>>.........<<......>>...>>>>>.>.>>>>>>
>>>>>>>..........))).>....>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<
...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<
<<....>>>........<<<<<......>>>>>....>>>....>>...<
<<<<........>>>>>))<<<<.<<<<.<<<....<<<....>>>....
...<<<<<<...<<<<.<<<<<<<<<<<<<.<<<<...((..>>>>.><.
..<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>
>>....><<<<<<<<....>>>>>>>>>>>>.>.>>>>>>>.>>>>....
.....>>>>>>.........>>>...>>>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<
.<<.......<.<<<<<<.<.<<.................<<<<<.<<<<
<..<.<<<..<<<<....<<<<<<<<.<<.<<<<<<<.<<.<<<<<....
>>>>>.>>.>>>>>>>.>>.>>>>>>>>....>>>>..>>>>...>>>>>
......>>>>>......>>...>.>>>>>>....>...>>.>>>>>>>..
>>>>>>....>>....<<<<<........>>>>>....<<<<<..<<<..
......<<<<<<.<<<<<<.<<<<<.<<<<<<<<..<<<<<<<<<<<<<<
<<<..........<<<<<......................>>>>>.>>>>
>>>.>>>>>>>>>>...<<<<...>>>>.....>>>>>>>>..>>>>>..
<<<<<<..<<<<<<...>>>>>>>>>>>>.....>>>>>.>.>>>>>>..
.((........<<<<<<...<<.......>>...>>>>>>((....<<<<
.<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.<...))>.>>>
.....>>>>>)).>>>>.<<<<<<<....>>>.>>>>....>>>.>>>>>
....<<<<<<<..<<<<.<.<<<<<.................>>>>>.><
<<<<...<<<<....<<<<<<<<<<))..>>>>>..>>>>>...>>>>..
>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>....
>>>>>>>.....<<<<<.<<.<<<......<<.......<<<....>>>.
...>>........<<<<.....<<<.<<<<<.......>>>>>.>>>...
.>>>>..............>>>>>.>>>>>...<<<<<<<..........
...>>....<<<<<<<<<.<<<....<<<<.<..<<<<<......>>>>>
..>>>>>...>>>....>>>>..>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9z Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
K24 N27 F28 L29 Q35 Q44 R60 K130 C164 K207 M210
Binding residue
(residue number reindexed from 1)
K21 N24 F25 L26 Q32 Q41 R57 K127 C161 K204 M207
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000470 maturation of LSU-rRNA
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8i9z, PDBe:8i9z, PDBj:8i9z
PDBsum8i9z
PubMed37129998
UniProtG0S4Z9

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