Structure of PDB 7zjx Chain Lm Binding Site BS01

Receptor Information
>7zjx Chain Lm (length=86) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK
Ligand information
>7zjx Chain L5 (length=3732) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcgguggggcgcgggaaau
guggcguacggaagacccacuccccggcgccgcucguggggggcccaagu
ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc
ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca
gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac
cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga
gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg
caguccgcccggaggauucaacccggcggcgugguccggccgugccggcg
gucucggcggaucuuucccgcuccggggucggcgggggaccgccccccgg
ccggcgaccggccgccgccgggcgcauuuccaccgcggcggugcgccgcg
accggcuccgggacggcugggaaggccccggcggggaagguggcccgggg
ggacgccucgccggcgggcgcgaccccuccccggguguuacagccccgcc
ccggcagcagcagcucgccgaaucccggggccgagggagcgagaccugug
ucgccgcgcucuccccccucgggggggccgggccgccccucccacggcgc
gaccgcucggggcggacuguccccagugcgccccgggcgugucacgccgu
cgggcucgggggaggccacggcgcgucgcgcgccggcgcgcgcgcgcgag
cgagcgcacggggucggcggcgaugucggcuacccacccgacccgucuug
aaacacggaccaaggagucuaacacgugcgcgagucgggggcucgcacga
aagccgccguggcgcaaugaaggugaaggccggcggcggcgccgucgucg
gccgaggugggaucccgaggcccuuccaguccgccgagggcgcaccaccg
gcccgucucgcccgccgcgccggggagguggagcacgagcgcacguguua
ggacccgaaagauggugaacuaugccugggcagggcgaagccagaggaaa
cucugguggagguccguagcgguccugacgugcaaaucggucguccgacc
uggguauaggggcgaaagacuaaucgaaccaucuaguagcugguucccuc
cgaaguuucccucaggauagcuggcgcucucgcaaccccgcaguuuuauc
cgguaaagcgaaugauuagaggucuuggggccgaaacgaucucaaccuau
ucucaaacuuuaaauggguaagaagcccggcucgcuggcguggagccggg
cguggaaugcgagugccuagugggccacuuuugguaagcagaacuggcgc
ugcgggaugaaccgaacgccggguuaaggcgcccgaugccgacgcucauc
agaccccagaaaagguguugguugauauagacagcaggacgguggccaug
gaagucggaauccgcuaaggaguguguaacaacucaccugccgaaucaac
uagcccugaaaauggauggcgcuggagcgucgggcccauacccggccguc
gcuggcagucggcagagcgagaaagagaguggagccgcggacgcuacgcc
gcgacgaguaggagggccgcugcggugagccuugaagccuagggcgcggg
cccggguggagccgccgcaggugcagaucuuggugguaguagcaaauauu
caaacgagaacuuugaaggccgaaguggagaaggguuccaugugaacagc
aguugaacaugggucagucgguccugagagaugggcgagcgccguuccga
agggacgggcgauggccuccguugcccucagccgaucgaaagggagucgg
guucagauccccgaauccggaguggcggagaugggcgccgcgaggcgucc
agugcgguaacgcgaccgaucccggagaagccggcgggagccccggggag
aguucucuuuucuuugugaagggcagggcgcccuggaauggguucgcccc
gagagaggggcccgugccuuggaaagcgucgcgguuccggcggcguccgg
ugagcucucgcuggcccuugaaaauccgggggagaggguguaaaucucgc
gccgggccguacccauauccgcagcaggucuccaaggugaacagccucug
gcauguuggaacaauguagguaagggaagucggcaagccggauccguaac
uucgggauaaggauuggcucuaagggcugguagcagccgacuuagaacug
gugcggaccaggggaauccgacuguuuaauuaaaacaaagcaucgcgaag
gcccgcggcggguguugacgcgaugugauuucugcccagugcucugaaug
ucaaagugaagaaauucaaugaagcgcggguaaacggcgggaguaacuau
gacucucuuaagguagccaaaugccucgucaucuaauuagugacgcgcau
gaauggaugaacgagauucccacugucccuaccuacuauccagcgaaacc
acagccaagggaacgggcuuggcggaaucagcggggaaagaagacccugu
ugagcuugacucuagucuggcacggugaagagacaugagagguguagaau
aagugggaggcccgggccgccggugaaauaccacuacucuuaucguuuuu
ucacugacccggugaggcgggggggcgagccccgaggggcucucgcuucu
ggcgccaagcgccgggccccgucgguccgggccggcggcggccgggcgcg
acccgcuccggggacagugccagguggggaguuugacuggggcgguacac
cugucaaacgguaacgcagguguccuaaggcgagcucagggaggacagaa
accucccguggagcagaagggcaaaagcucgcuugaucuugauuuucagu
acgaauacagaccgugaaagcggggccucacgauccuucugagcuuuugg
guuuuaagcaggaggugucagaaaaguuaccacagggauaacuggcuugu
ggcggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggc
ucuuccuaucauugugaagcagaauucaccaagcguuggauuguucaccc
acuaauagggaacgugagcuggguuuagaccgucgugagacagguuaguu
uuacccuacugaugauguguuguugccaugguaauccugcucaguacgag
aggaaccgcagguucagacauuugguguaugugcuuggcugaggagccaa
uggggcgaagcuaccaucugugggauuaugacugaacgccucuaagucag
aaucccgcccaggcggaacgauacggcagcgccgaaggagccucgguugg
ccucggauagccggucccccgcgggguccggugcggagagcccuucgucc
cgggaaauggggcgcggccggaaagggggccgcccucucgcccgucacgc
accgcacguucguggggaaccuggcgcuaaaccauucguagacgaccugc
uucugggucgggguuucguacguagcagagcagcucccucgcugcgaucu
auugaaagucagcccucgacacaaggguuugu
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..<<<..<<<<<...<<<<<<<<<<.....>>>>>>.>>>>...
..>>>>>..<<<<<<<<<....<<<<<<<<.<<<....<<<<<<<<....
<<<<......>>>>.....((......<<<.....))>>>...>.>>>>>
>>>>>>>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>
>>>>.....<<<<<..((((((>>>>>..>>>..................
................<<....>>...............<<<<....>>>
>..................................<<<<<<<<..<<<.<
<...<<<<<<<<.<<<.....<<<<<<<<<<....<<<<<<<.<<<<<.<
.....<<<<<.<<<..<<<<.<.........>>>>>>>>>>>>>.>>>>>
>>>>>...>>>.>>>>>>>>>>......>>>.>>>.>>>>>...<<<<<<
<.<<<<<<<<<<.<<<<...<<..<<<..<<<<<<<......<<<<.<<<
<<.......<....>...........>>.>>>>>>>.......>>>>>>>
..>>>.........>>>>>>...>>>>>>>>>>.....<<.....[[>>.
.....<<<<<..<<<<<<<.>>>>>>>...<<<<.<<<<.<<<<<<<<<.
<<<<<<.....<<<.<<<<....>>>>.>>>.....>>>.>>>.>>>>>>
.>>>...>>>>..>>>>...<<<....<<..........>>...>>>...
..>>>>>......>>.>>>>>...>>>>>...>>>>>>>>..<<<<....
....>>>><<<<<<...<<<<<<<<<<<<<<..<<<...<<<<.......
.>>>>.....>>>...<<....>>...<<<<<<<<<.<<..>>.>>>>>>
>>>..<<<<<...<<<..<<....{{...{{..>>..>>>....>>>>>.
<<<<<<<<<.<<<<......>>>>>>>>>>>.>>....>>>>>>>>>>>>
>>.<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....
>>>>>>>.....>>>...<<<..<<.<<........>>>>.>>>....>>
>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<<<<<
<....<.<<<....>>>.><<.<<<<<<<..........<<<.<<<<<<<
<<...<<<....<<<..<.<<<..<<<<<<.<.....>.>>>>>>>>>.>
..>>>..>>.>...>>>>>>>...<<<<<<<<<.........>>>>>>>>
>....>>>>>>>>>>>>..>>..<<<<.<<<<<.....>>>>>.>>>>..
..<<<......>>>...<<<<<<<...<<<(((.......<<<<<.....
<<..........<<<.<<<<<<<<<<.......<<<<<..<....<<...
......>>....>..........<<......>>...>>>>>...>>>>>>
>>>>>>>..........))).>>...>>>>>..>>>...>>>>>>><<<<
<<.<<<.......]]...........}}...}}..............>>>
>>>>>>....>>>>>>...<<<<<<<<.<<......<<<<.<<<<....>
>>>>>>>...>>>>>>>>>>........>>>>>><<.....<<.....<<
<<<<.......>>>>>>.<<<.....<<<<<.<<...<<<<<<...<<..
...>>.>>>>>>....((<<<<<<...<<....<<<....>>>.......
...<<.<<<<<<<<<...>>>>>>>>>>>......>>....>>>..<<<<
<........>>>>>))<<<<....<<<<<..<<<<<<<<....>>>>>>>
>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<<<.<<<<<<<<
<<..[[[..>>>>>>....<<<<<.<<<<.<<<<.....<<<.....>>>
.....>>>>>>>>..>>>>>.....<<<<<<<.......>>>>>>>>>>>
...>>>>>>>>>>>>.........>>>>>>>..>..........>>.>>>
.>>>>.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>
>>....<<<<.....<<<<<<<.<<...............<<<<<....<
....>.....>>>>><<.<<<<<<<<<<<....>>>>>..>>>>>>.>>.
...........<<<<<<<<<..<<<.........>>>..<<<<<<<....
<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<....<<
<.....<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<......
.>>>>>>........<...........<<<<<.......>>>>>.....>
.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>....>>
....<<<<<........>>>>>....<<<<<..<<<.<<......<<<<.
<<<<<<..<<<<..<<<<<<<<<.<<<<<<.<<<<<<<<<..........
.<<<<<..<<<<..>>>>............>>>>>..>>>>>>.>>>.>>
>>>>...<<<<<.....<<<<.....<<<<<<....>>>>>>........
........<<<<<..<<...<<...<<..>>...>>....>>..>>>>>.
.>>>>..>>>>>....>>>>>>>>>...>>>>...<<<.....>>>..<<
<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<......
.>>>>>>.....<<.[.(((>>....>>>>>>>...<<<..<<<<.....
..>>>>..>>><<<<....>>>>>>)))].....<<<<<<<..<<<..))
)))).>>>>>>>>>>.........>>>>..>>>>>>.......<<.<...
<<<<<<...<<.......>>...>>>>>>....>.>.>.......<<<<<
.<<<<<<..<.<.<<<<<......>>>>>...>.>.<<<.........>>
>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....
>>..>>>.>>>>>.....<<<<<<.<..<<<..<.<<<<<..........
.......>>>>>.><<<<....<<<<....<<.<<<<<<<]]].>>>>>.
.>>.>>...>>>>...>>>><<<<<...<<<<<...........>>>>>.
..>>>>>.>>>...>.>>>>>>.....<<<<<<<..<<..<<<<....<<
<........<<<<<..<<<<..>>>>.>>>>>.......>>>...<<<..
<<<<....<<<<.<<<<<..........>>>>>>>>>...>>>>..>>>.
.............>>>>..>>>>>>>>><<<<<.................
...<<.<<<<<<<.<<.....<<<<.<..<<<<<......>>>>>..>>>
>>....>>....>>>>.>>>.>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zjx Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
T2 K3 G4 T5 S6 F8 G9 K10 R11 R12 N13 K14 T15 H16 K25 Q30 G35 R43 K44 R45 K46 Y47 N48 W49 K52 R55 R56 T58 T59 Y71 G81 K85
Binding residue
(residue number reindexed from 1)
T1 K2 G3 T4 S5 F7 G8 K9 R10 R11 N12 K13 T14 H15 K24 Q29 G34 R42 K43 R44 K45 Y46 N47 W48 K51 R54 R55 T57 T58 Y70 G80 K84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7zjx, PDBe:7zjx, PDBj:7zjx
PDBsum7zjx
PubMed35709277
UniProtU3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)

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