Structure of PDB 9fpz Chain Lk Binding Site BS01

Receptor Information
>9fpz Chain Lk (length=69) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKE
KAEKLKQSLPPGLAVKELK
Ligand information
>9fpz Chain 1 (length=300) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaguccuucugaucgaggcccagcccguggacggugugaggccgguagu
ugaaaagaacuuugaagagagaguucaagagggcgccgcccggaggauuc
aacccggcggcggguccggccgugucggcggcccggcggaucuuucccgc
gcgggggaccgucccccgaccggcgaccggccgccgccgggcgcauuucc
accgcggcgguucaaacgagaacuuugaaucggguucagauccccgaauc
uuggaaagcgucgcgguuccggcggcguaagggcugguagcagccgacuu
<....<<<<......>>>>.....((......<<<.....))>>>...>.
.........<<<<....>>>>..............<<<<<<<<.<<<...
..<<<<<<<<<<<..<<<<<<<..<....<.....<<<<.<<<..<<<..
..>>>>>>>>>>.>...>..>>>>...>>>>>>>>>>>>>>......>>>
.>>>.>>>>><<<<<<.......>>>>>><<<<<........>>>>>...
.......<<<<<<<.......>>>>>>><<<<<<<<....>>>>>..>>>
Receptor-Ligand Complex Structure
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PDB9fpz Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome
Resolution2.69 Å
Binding residue
(original residue number in PDB)		P2 K4 K26 N28 K33 K35 R37 Y41 L42 T44 L69
Binding residue
(residue number reindexed from 1)		P1 K3 K25 N27 K32 K34 R36 Y40 L41 T43 L68
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
GO:0007605 sensory perception of sound
GO:0022618 protein-RNA complex assembly
GO:0034463 90S preribosome assembly
GO:0042474 middle ear morphogenesis
GO:0048318 axial mesoderm development
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0014069 postsynaptic density
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0033291 eukaryotic 80S initiation complex
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9fpz, PDBe:9fpz, PDBj:9fpz
PDBsum9fpz
PubMed
UniProtP63173|RL38_HUMAN Large ribosomal subunit protein eL38 (Gene Name=RPL38)

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