Structure of PDB 8onz Chain Lk Binding Site BS01

Receptor Information

>8onz Chain Lk (length=76) Species: 759272 (Thermochaetoides thermophila DSM 1495)

PQEVSDIKKFIEICRRKDASSARIKKNPKTQQIKFKVRCQRFLYTLVLKD
SDKAEKLKQSLPPNLQIKDVPKRNKR

Ligand information

>8onz Chain 1 (length=270)

augaaaagcacuuugaaaagaggguuaaauagcaccuucaaugagaacuu
gaaguuccaugugaacagcgguuggacauggguugccgguuaauauuccg
gcacccggaagagcccgacacuucugucgggucaaggguugggcacguug
ggcuuugggcgcgcccugggagcagagggccucuagccgggcaaccggcc
ggcggcccucagcacccgggguagcccuuagcaggcuucggccguccggc
gugcgguuaacaaccaacuu

..........<<<<....>>>>.............<<<<<<.......>>
>>>>..<<<<<<...<<.....>>.>>>>>>...<<<<<........>>>
>>..........<<<<<<<......>>>>>>>.<<<<<<<<.<<<<<<<.
..<<..<<<<...<<<<<<<.<<.<<<<<<<.<<.<<<<<....>>>>>.
>>.>>>>>>>.>>.>>>>>>>..>>>>..>>..<<<....>>>....>>>
>>>>......>>>>>..>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8onz Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
• Resolution: 2.94 Å
• Binding residue (original residue number in PDB): P2 E4 R24 K26 K30 K35 K37 R39 R42 F43 L44 T46 V71 K73 R74 N75
• Binding residue (residue number reindexed from 1): P1 E3 R23 K25 K29 K34 K36 R38 R41 F42 L43 T45 V70 K72 R73 N74

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation
• GO:0022618 protein-RNA complex assembly

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8onz, PDBe:8onz, PDBj:8onz
• PDBsum: 8onz
• PubMed: 38267453
• UniProt: G0SG89