Structure of PDB 8ony Chain Lk Binding Site BS01

Receptor Information
>8ony Chain Lk (length=69) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKE
KAEKLKQSLPPGLAVKELK
Ligand information
>8ony Chain 5 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaaaagaacuuugaagagagaguucaagagggcguucaaacgagaacu
uugaauuccaugugaacagcaguugaacaugggucucggguucagauccc
cgaaucuuggaaagcgucgcgguuccggcggcguaagggcugguagcagc
cgacuu
..........<<<......>>>..............<<<<<<.......>
>>>>>..<<<<<<...<<.....>>.>>>>>>...<<<<<........>>
>>>..........<<<<<<<.......>>>>>>><<<<<<<<....>>>>
>..>>>
Receptor-Ligand Complex Structure
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PDB8ony Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		P2 K24 K26 K33 K35 R37 Y41 L69
Binding residue
(residue number reindexed from 1)		P1 K23 K25 K32 K34 R36 Y40 L68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
GO:0007605 sensory perception of sound
GO:0022618 protein-RNA complex assembly
GO:0034463 90S preribosome assembly
GO:0042474 middle ear morphogenesis
GO:0048318 axial mesoderm development
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0014069 postsynaptic density
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0033291 eukaryotic 80S initiation complex
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ony, PDBe:8ony, PDBj:8ony
PDBsum8ony
PubMed38267453
UniProtP63173|RL38_HUMAN Large ribosomal subunit protein eL38 (Gene Name=RPL38)

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