Structure of PDB 8i9y Chain Lk Binding Site BS01

Receptor Information
>8i9y Chain Lk (length=75) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQEVSDIKKFIEICRRKDASAARIKKNPKTQQIKFKVRCQRFLYTLVLKD
SDKAEKLKQSLPPNLQIKDVPKRNK
Ligand information
>8i9y Chain C1 (length=2609) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuaugcuuggauagggug
aagccagaggaaacucugguggaggcucgcugacgugcaagaucgucaaa
ucugagcaugggggcgaaagacuaaccaucuaguagcugguuaccgccga
aguuucccucaggauagcagugucgaccuucaguuuuaugagguaaagcg
aaugaacuuuaaauauguaagaagcccuuguuacuuaacugaacgugggc
auucgaauguaucgacacuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacgcgggguuaaggugccggaguggacgcucauc
agacaccacaaaaggcguuaguacaucuugacagcaggacgguggccaug
gaagucggaauccgcuaaggacuguguaacaacucaccugccgaauguac
uagcccugaaaauggauggcgcucaagcgucccacccauaccccgcccuc
aggguagaaacgaugcccugaggaguaggcggccguggaggucagugacg
aagccuagggcgugagcccgggucgaacggccucuagugcagaucuuggu
gguaguagcaaauacuucaaugagaacuugaaggaccgaaguggggaaag
guuccaugugaacagcgguuggacauggguuagucgauccuaagccauag
ggaaguuccguuucaaaggggcacucgugccccguguggcgaaagggaag
ccgguuaauauuccggcaccuggauguggguuuugcgcggcaacgcaacu
gaacgcggagacgacggcgggggccccgggcagaguucucuuuucuucuu
aacggucuaucacccuggaaacaguuugucuggagauaggguuuaauggc
cggaagagcccgacacuucugucggguccggugcgcucucgacgucccuu
gaaaauccgcgggagggaauaauucucacgccaggucguacucauaaccg
cagcagguccccaaggugaacagccucugguugauagaacaauguagaua
agggcugucccuaucuacuaucuagcgaaaccacagccaagggaacgggc
uuggcaaaaucagcggggaaagaagacccuguugagcuugacucuaguuu
gacauugugaaaagacauaggagguguagaauaggugggagcuucggcgc
cagugaaauaccacuacuccuauuguuuuuuuacuuauucaaugugaaga
cauugucagguggggaguuccuuuagucccucgaaauuugaggcuagagg
agaaaaguuaccacagggauaacuggcuuguggcggccaagcguagcgac
gucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauucggua
agcguuggauuguucacccacuaauagggaacgugagcuggaccgucgug
agacagguuagucccuacugaugaacucgucgcaaugguaauucagcuua
guacgagaggaaccgcugauucagauaauugguuuuugcgguuguccgac
cgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccucu
aagucagaauccaugccagaacgcgacgauacuacccgcacguuguagac
guauaagaauaggcuccggccucguauccuagcaggcgauuccuccgccg
gccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgcg
ggaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaagc
aguagaguagccuuguuguuacgaucugcugaggguaagcccuccuucgc
cuagauuuc
........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<........>>>><<<<<<....<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<...<<<<<<...<.<<<<<<<<<..<<<<.
..<<<<<<<....>>>>>>>...>.>>>..<<<<<........>>>>>..
>>>>>>>>>>.<<.<....>.>>.>>>>>>......>.>>...<<<<<..
..<.<<<....>>>.><<<<<<<<<<....<<.<<<<<<<.....<<<..
......>>.>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<...<<<((......<<<<<<.....
<<..........<<<.<<<<<<<<<<.......<<<<<.<<<...<<...
......>>...>>>.........<<......>>...>>>>>...>>>>>>
>>>>>>>...........)).>>...>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<
...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<
<<....>>>........<<<<<......>>>>>....>>>....>>...<
<<<<........>>>>>))<<<<.<<<<.<<<....<<<....>>>....
...<<<<<<...<<<<.<<<<<<<<<<<<<.<<<<...((..>>>>.><.
..<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>
>>....><<<<<<<<....>>>>>>>>>>>>.>.>>>>>>>.>>>>....
.....>>>>>>.........>>>...>>>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<.
<<<......>>>>>>>>>..>>>>>>....>>....<<<<<........>
>>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.<<<<
<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....>>..
..........>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>>>..
...>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>>
....>>>>>.>.>>>>>>.............<<<<<<...<<...>>...
>>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>>>>>
...>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<<...
.>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<...
..............>>>>>.><<<<<...<<<<....<<<<<<<<<<)).
.>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<..........
.>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<....
..<<.......<<<....>>>....>>........<<<<.....<<<.<<
<<<.......>>>>>.>>>....>>>>..............>>>>>.>>>
>>...<<<<<<<.............>>....<<<<<<<<<.<<<....<<
<<.<..<<<<<......>>>>>..>>>>>...>>>....>>>>..>>>>>
...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
P2 E4 R24 K26 K35 K37 R39 R42 F43 L44 T46 V71 K73 R74
Binding residue
(residue number reindexed from 1)
P1 E3 R23 K25 K34 K36 R38 R41 F42 L43 T45 V70 K72 R73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8i9y, PDBe:8i9y, PDBj:8i9y
PDBsum8i9y
PubMed37129998
UniProtG0SG89

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