Structure of PDB 8i9w Chain Lj Binding Site BS01

Receptor Information
>8i9w Chain Lj (length=74) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTHGLCRRCGRRSLHNQKKVCASCGYPAAKTRKYNWSEKAKRRKVTGTGR
MRYLSTVPRRFKNGFRTGVPKGAR
Ligand information
>8i9w Chain C1 (length=2163) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuauaugggggcgaaaga
cuaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcagu
gucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaag
aagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacuag
ugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcg
ggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguuag
uacaucuugacagcaggacgguggccauggaagucggaauccgcuaagga
cuguguaacaacucaccugccgaauguacuagcccugaaaauggauggcg
cucaagcgucccacccauaccccgcccucaggguagaaacgaugcccuga
ggaguaggcggccguggaggucagugacgaagccuagggcgugagcccgg
gucgaacggccucuagugcagaucuuggugguaguagcauagaacaaugu
agauaagggaagucggcuccguaacuugguacggacaggggaaucugcga
gauucccacugucccuaucuacuaucuagcgaaaccacagccaagggaac
gggcuuggcaaaaucagcggggaaagaagacccuguugagcuugacucua
guuugacauugugaaaagacauaggagguguagaauaggugggagcuucg
gcgccagugaaauaccacuacuccuauuguuuuuuuacuuauucaaugug
aagacauugucagguggggaguuccuuuagucccucgaaauuugaggcua
gaggagaaaaguuaccacagggauaacuggcuuguggcggccaagcguag
cgacgucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauuc
gguaagcguuggauuguucacccacuaauagggaacgugagcuggaccgu
cgugagacagguuagucccuacugaugaacucgucgcaaugguaauucag
cuuaguacgagaggaaccgcugauucagauaauugguuuuugcgguuguc
cgaccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgc
cucuaagucagaauccaugccagaacgcgacgauacuacccgcacguugu
agacguauaagaauaggcuccggccucguauccuagcaggcgauuccucc
gccggccucgaaguggccgucgguaauucgcguauugcaauuuagacacg
cgcgggaucaaauccuuugcagacgacuuagaugugcgaaaggguccugu
aagcaguagaguagccuuguuguuacgaucugcugaggguaagcccuccu
ucgccuagauuuc
........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.....<.<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>....>.>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<....<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<...<<<<<<...<.<<>>>.<<.<....>.
>>.>>>>>>......>.>>...<<<<<....<.<<<....>>>.><<<<<
<<<<<....<<.<<<<<<<.....<<<........>>.>.....>>>>>.
..<<<<.<<<<.<......>>>>>.>>>>.....>>>>..>>>>>>>>.>
>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<
<<<<...<<<.(......<<<<<<.....<<..........<<<.<<<<<
<<<<<.......<<<<<.<<<...<<.........>>...>>>.......
..<<......>>...>>>>>...>>>>>>>>>>>>>...........)..
>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>
>>....>>>>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>>
>>...>>>>>>>>>>........>>>>>><<.....<<.<<<<.....<<
<<<<.<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>>.
>>>>>>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<.....
...>>>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.
<<<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....
>>............>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>
>>.....>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>
>>>>....>>>>>.>.>>>>>>.............<<<<<<...<<...>
>...>>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>
>>>>...>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<
<....>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<
<.................>>>>>.><<<<<...<<<<....<<<<<<<<<
<....>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<......
.....>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<
......<<.......<<<<..>>>>....>>........<<<<.....<<
<.<<<<<.......>>>>>.>>>....>>>>..............>>>>>
.>>>>>...<<<<<<<.............>>....<<<<<<<<<.<<<..
..<<<<....<<<<<......>>>>>...>>>>...>>>....>>>>..>
>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9w Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		T15 H16 R24 S26 H28 K31 A35 K43 T44 R45 K46 Y47 N48 W49 K52 R55 R56
Binding residue
(residue number reindexed from 1)		T2 H3 R11 S13 H15 K18 A22 K30 T31 R32 K33 Y34 N35 W36 K39 R42 R43
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9w, PDBe:8i9w, PDBj:8i9w
PDBsum8i9w
PubMed37129998
UniProtG0S101

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