Structure of PDB 7old Chain Lj Binding Site BS01

Receptor Information
>7old Chain Lj (length=88) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRHNKTHGLCRRCGRRSLHNQKKVCASCGYPAAKTRKYNWSE
KAKRRKVTGTGRMRYLSTVPRRFKNGFRTGVPKGARGP
Ligand information
>7old Chain 1 (length=3192) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guugaccucggaucagguaggaggacccgcugaacuuaagcauaucaaua
agcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaag
cggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugg
agaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcc
acagagggugagagccccguauaguuggaagccaagccuguguaaagcuc
cuucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaau
uucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagu
gaucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaa
uuguugaaagggaagcgcuugugaccagacuugcgcccggcggaucaucc
gguguucucaccggugcacuccgccgggcucaggccagcaucgguucugg
cggggggauaaaggcccagggaauguggcuccuccgggaguguuauagcc
cuggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugc
uggcguaauggucaccagcgacccgucuugaaacacggaccaaggaguca
agguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaagug
aacguaggugagagcuucggcgcaucaucgaccgauccugauguauucgg
auggauuugaguaggagcguuaagccuuggacccgaaagauggugaacua
ugcuuggauagggugaagccagaggaaacucugguggaggcucgcagcgg
uucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacua
aucgaaccaucuaguagcugguuaccgccgaaguuucccucaggauagca
gugucgaccuucaguuuuaugagguaaagcgaaugauuagggacucgggg
gcgauuuuuagccuucauccauucucaaacuuuaaauauguaagaagccc
uuguuacuuaacugaacgugggcauucgaauguaucgacacuagugggcc
auuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcgggguua
aggugccggaguggacgcucaucagacaccacaaaaggcguuaguacauc
uugacagcaggacgguggccauggaagucggaauccgcuaaggacugugu
aacaacucaccugccgaauguacuagcccugaaaauggauggcgcucaag
cgucccacccauaccccgcccucaggguagaaacgaugcccugaggagua
ggcggccguggaggucagugacgaagccuagggcgugagcccgggucgaa
cggccucuagugcagaucuuggugguaguagcaaauacuucaaugagaac
uugaaggaccgaaguggggaaagguuccaugugaacagcgguuggacaug
gguuagucgauccuaagccauagggaaguuccguuucaaaggggcacucg
ugccccguguggcgaaagggaagccgguuaauauuccggcaccuggaugu
ggguuuugcgcggcaacgcaacugaacgcggagacgacggcgggggcccc
gggcagaguucucuuuucuucuuaacggucuaucacccuggaaacaguuu
gucuggagauaggguuuaauggccggaagagcccgacacuucugucgggu
ccggugcgcucucgacgucccuugaaaauccgcgggagggaauaauucuc
acgccaggucguacucauaaccgcagcagguccccaaggugaacagccuc
ugguugauagaacaauguagauaagggaagucggcaaaauagauccguaa
cuucgggaaaaggauuggcucuaaggguugggcacguuggcggcgugcgg
uuaacaaccaacuuagaacugguacggacagggggaaucugacugucuaa
uuaaaacauagcauugcgauggccagaaagugguguugacgcaaugugau
uucugcccagugcucugaaugucaaagugaagaaauucaaccaagcgcgg
guaaacggcgggaguaacuaugacucucuuaagguagccaaaugccucgu
caucuaauuagugacgcgcaugaauggauuaacgagauucccacuguccc
uaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaauc
agcggggaaagaagacccuguugagcuugacucuaguuugacauugugaa
aagacauaggagcuccuauuguuuuuuuacuuauucaaugaagcggggcu
ggacuugcguccaacuucuggaguuaagguccuucgcgggccgacccggg
uugaagacauugucagguggggaguuuggcuggggcggcacaucuguuaa
accauaacgcagguguccuaaggggggcucauggagaacagaaaucucca
guagaacaaaaggguaaaaguccccuugauuuugauuuucagugugaaua
caaaccaugaaaguguggccuaucgauccuuuagucccucgaaauuugag
gcuagaggugccagaaaaguuaccacagggauaacuggcuuguggcggcc
aagcguucauagcgacgucgcuuuuugauccuucgaugucggcucuuccu
aucauaccgaagcagaauucgguaagcguuggauuguucacccacuaaua
gggaacgugagcuggguuuagaccgucgugagacagguuaguuuuacccu
acugaugaacucgucgcaaugguaauucagcuuaguacgagaggaaccgc
ugauucagauaauugguuuuugcgguuguccgaccgggcagugccgcgaa
gcuaccaucugcuggauaauggcugaacgccucuaagucagaauccaugc
cagaacgcgacgauacuacccgcacguuguagacguauaagaauaggcuc
cggccucguauccuagcaggcgauuccuccgccggccucgaaguggccgu
cgguaauucgcguauugcaauuuagacacgcgcgggaucaaauccuuugc
agacgacuuagaugugcgaaaggguccuguaagcaguagaguagccuugu
uguuacgaucugcugaggguaagcccuccuucgccuagauuu
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<......<<.....>>....
.>>>>>..[[[..<<.......<<.<<<<..>>>>.>>.......>>...
.<<<<<.<<<<<<<<<..<<<<<<........<<<<......>>>>.((.
.....<<<.....))>>>........>>.>>>>..>>>>....>>>>>>>
>.>>........<<<<<<<........>>>>>>>.....(((((..<<<<
<<)))))..]]]..................................<<..
..>>...............<<<<....>>>>...................
...............<<<<.<<<<<<.....<<.<<<<<<<<<.....<<
<<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<
<<<<<<.....<.<<<<<<<<......<<<<<....>>>>>.......>>
>>>>>>....>.>>>>>>>>>>>>>>>........<<...>>.....>>>
>>>>.....>>>>>>.>>>>..<<<<........>>>><<<<<<....<<
<<<<<<.<<<<..<<<...<<<<.....>>>>...>>>...<<....>>.
......<<<<<..<<<..>>>...>>>>>.<<<<<<<<...<<....>>.
..>>>.>>>.>>....>>>>.>>>>>>>>..<<.<...<<<<<<.....<
<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<.
.<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>.
.....>>>>>>......>.>>...<<<<<....<.<<<....>>>.><<<
<<<<<<.....<<.<<<<<<<.....<<<....<<<..<.<<<...<<<<
<<........>>>>>>.>>>.>..>>>..>>.>.....>>>>>...<<<<
.<<<<.<......>>>>>.>>>>.....>>>>...>>>>>>>.>>..<<<
<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<..
.<<<(((.....<<<<<<.....<<..........<<<.<<<<<<<<<<.
......<<<<<.<<<...<<.........>>...>>>.........<<..
....>>...>>>>>...>>>>>>>>>>>>>..........))).>>...>
>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>>>....
>>>>>.<.<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...>
>>>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<.......
>>>>>><<<<.....<<<<<.<<...<<<<<....<<.....>>..>>>>
>....((<<<<<<...<<<...<<<....>>>........<<<<<.....
.>>>>>....>>>....>>...<<<<<........>>>>>))<<<<.<<<
<.<<<....<<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<
<<<.<<<<.......>>>>.><...<<<<<....<<<<<<....<<<...
..>>>....>>>>>>.....>>>>>....><<<<<<<......>>>>>>>
>>>>...>>>>>>>.>>>>.........>>>>>>.........>>>...>
>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>.
.>>>>..<<<<.....<<<<<<<.<<.........<.....<<<<<....
<<..>>.....>>>>><<.<<<<<<<<<<<.......<....>.......
....>>>>>..>>>>>>.>>............<<<<<<<<<..<<<....
.....>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...
<<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>>>.>>
>>..>>>>><<<<<<.......>>>>>>........<...........<<
<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>..>>.
>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....[[[
[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<<<..<<<<<
<<<<<<<<<<<..>>>>>.>>>>>>>>>>>...<<<<<.....<<<<..<
<<<<....>>>>>..............<<<<<.....>>>>>..>>>>..
>>>>>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>
.....<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.
>>>>.<<<....>>>.>>))).......((((((..((((.>>>>>>)))
)))))))..........]]]]..}}]]]].......<<.<.<.<<<<<<.
..<<.......>>...>>>>>>...>>..>>.......<<<<<.<<<<<<
..<.<<<<<<<......>>>>>>>...>.<<<.........>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....}}..}}}
.]]]]]....<<<<<<<..<<<<.<.<<<<<.................>>
>>>.><<<<<...<<<<....<<<<<<<<<<....>>>>>..>>>>>...
>>>>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>
>>....>>>>>>>.....<<<<<....<<<......<<.......<<...
....>>...>>........<<<<.....<<<.<<<<<.......>>>>>.
>>>....>>>>..............>>>...>>>>>...<<<<<<<....
.........>>....<<<<<<<<<.<<<....<<<<.<..<<<<<.....
.>>>>>..>>>>>...>>>....>>>>..>>>>>...>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7old High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
T2 K3 T5 F8 G9 R11 H12 N13 T15 H16 R24 R25 H28 Q30 A35 K43 T44 R45 K46 N48 W49 K52 R55 R56
Binding residue
(residue number reindexed from 1)
T1 K2 T4 F7 G8 R10 H11 N12 T14 H15 R23 R24 H27 Q29 A34 K42 T43 R44 K45 N47 W48 K51 R54 R55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7old, PDBe:7old, PDBj:7old
PDBsum7old
PubMed35079002
UniProtG0S101

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