Structure of PDB 8i9x Chain Li Binding Site BS01

Receptor Information
>8i9x Chain Li (length=88) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHKTTRRVLKERPSRRKGAQSKRTQFVRSLIREVAGLAPYERRVIELLRN
GKDKRARKFSKKKLGTFGRAKRKCEELQRIIAESRRAH
Ligand information
>8i9x Chain C1 (length=2658) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuaugcuuggauagggug
aagccagaggaaacucugguggaggcucgcugacgugcaagaucgucaaa
ucugagcaugggggcgaaagacuaaccaucuaguagcugguuaccgccga
aguuucccucaggauagcagugucgaccuucaguuuuaugagguaaagcg
aaugaacuuuaaauauguaagaagcccuuguuacuuaacugaacgugggc
auucgaauguaucgacacuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacgcgggguuaaggugccggaguggacgcucauc
agacaccacaaaaggcguuaguacaucuugacagcaggacgguggccaug
gaagucggaauccgcuaaggacuguguaacaacucaccugccgaauguac
uagcccugaaaauggauggcgcucaagcgucccacccauaccccgcccuc
aggguagaaacgaugcccugaggaguaggcggccguggaggucagugacg
aagccuagggcgugagcccgggucgaacggccucuagugcagaucuuggu
gguaguagcaaauacuucaaugagaacuugaaggaccgaaguggggaaag
guuccaugugaacagcgguuggacauggguuagucgauccuaagccauag
ggaaguuccguuucaaaggggcacucgugccccguguggcgaaagggaag
ccgguuaauauuccggcaccuggauguggguuuugcgcggcaacgcaacu
gaacgcggagacgacggcgggggccccgggcagaguucucuuuucuucuu
aacggucuaucacccuggaaacaguuugucuggagauaggguuuaauggc
cggaagagcccgacacuucugucggguccggugcgcucucgacgucccuu
gaaaauccgcgggagggaauaauucucacgccaggucguacucauaaccg
cagcagguccccaaggugaacagccucugguugauagaacaauguagaua
agggaagucggcuccguaacuugguacggacaggggaaucugcgagauuc
ccacugucccuaucuacuaucuagcgaaaccacagccaagggaacgggcu
uggcaaaaucagcggggaaagaagacccuguugagcuugacucuaguuug
acauugugaaaagacauaggagguguagaauaggugggagcuucggcgcc
agugaaauaccacuacuccuauuguuuuuuuacuuauucaaugugaagac
auugucagguggggaguuccuuuagucccucgaaauuugaggcuagagga
gaaaaguuaccacagggauaacuggcuuguggcggccaagcguagcgacg
ucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauucgguaa
gcguuggauuguucacccacuaauagggaacgugagcuggaccgucguga
gacagguuagucccuacugaugaacucgucgcaaugguaauucagcuuag
uacgagaggaaccgcugauucagauaauugguuuuugcgguuguccgacc
gggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccucua
agucagaauccaugccagaacgcgacgauacuacccgcacguuguagacg
uauaagaauaggcuccggccucguauccuagcaggcgauuccuccgccgg
ccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgcgg
gaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaagca
guagaguagccuuguuguuacgaucugcugaggguaagcccuccuucgcc
uagauuuc
........................<<<<<<.....<<....>>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>>.<<.<..<<<<<<<...<.<<<<<<<<<..<<<<.
..<<<<<<<....>>>>>>>...>.>>>..<<<<<........>>>>>..
>>>>>>>>>>.<<.<....>.>>.>>>>>>>.....>.>>...<<<<<..
..<.<<<....>>>.><<<<<<<<<<....<<.<<<<<<<.....<<<..
......>>.>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<...<<<((......<<<<<<.....
.<..........<<<.<<<<<<<<<<.......<<<<<.<<<...<<...
......>>...>>>.........<<......>>...>>>>>...>>>>>>
>>>>>>>...........)).>....>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<
...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<
<<....>>>........<<<<<......>>>>>....>>>....>>...<
<<<<........>>>>>))<<<<.<<<<.<<<....<<<....>>>....
...<<<<<<...<<<<.<<<<<<<<<<<<<.<<<<...((..>>>>.><.
..<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>
>>....><<<<<<<<....>>>>>>>>>>>>.>.>>>>>>>.>>>>....
.....>>>>>>.........>>>...>>>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<.
<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>>.>>>>>
>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<........>>
>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.<<<<<
<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....>>...
.........>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>>>...
..>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>>.
...>>>>>.>.>>>>>>.............<<<<<<...<<...>>...>
>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>>>>>.
..>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<<....
>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<....
.............>>>>>.><<<<<...<<<<....<<<<<<<<<<))..
>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........
>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<.....
.<<.......<<<<..>>>>....>>........<<<<.....<<<.<<<
<<.......>>>>>.>>>....>>>>..............>>>>>.>>>>
>...<<<<<<<.............>>....<<<<<<<<<.<<<....<<<
<.<..<<<<<......>>>>>..>>>>>...>>>....>>>>..>>>>>.
..>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9x Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
G23 H24 T26 R34 P35 S36 K39 A41 S43 R45 R50 Y62 K85 L86 R91 R94
Binding residue
(residue number reindexed from 1)
G1 H2 T4 R12 P13 S14 K17 A19 S21 R23 R28 Y40 K63 L64 R69 R72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8i9x, PDBe:8i9x, PDBj:8i9x
PDBsum8i9x
PubMed37129998
UniProtG0SBN1

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