Structure of PDB 8i9v Chain Li Binding Site BS01

Receptor Information
>8i9v Chain Li (length=88) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHKTTRRVLKERPSRRKGAQSKRTQFVRSLIREVAGLAPYERRVIELLRN
GKDKRARKFSKKKLGTFGRAKRKCEELQRIIAESRRAH
Ligand information
>8i9v Chain C1 (length=2152) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacaac
caucuaguagcugguuaccgccgaaguuucccucaggauagcagugucga
ccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaagaagcc
cuuguuacuuaacugaacgugggcauucgaauguaucgacacuagugggc
cauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcgggguu
aaggugccggaguggacgcucaucagacaccacaaaaggcguuaguacau
cuugacagcaggacgguggccauggaagucggaauccgcuaaggacugug
uaacaacucaccugccgaauguacuagcccugaaaauggauggcgcucaa
gcgucccacccauaccccgcccucaggguagaaacgaugcccugaggagu
aggcggccguggaggucagugacgaagccuagggcgugagcccgggucga
acggccucuagugcagaucuuggugguaguagcaaauuugauagaacaau
guagauaagggaagucggcuccguaacuugguacggacaggggaaucugc
gagauucccacugucccuaucuacuaucuagcgaaaccacagccaaggga
acgggcuuggcaaaaucagcggggaagacccuguugagcuugacucuagu
uugacauugugaaaagacauaggagguguagaauaggugggagcuucggc
gccagugaaauaccacuacuccuauuguuuuuuuacuuauucaauugaag
acauugucagguggggaguuccuuuagucccucgaaauuugaggcuagag
gagaaaaguuaccacagggauaacuggcuuguggcggccaagcguucaua
gcgacgucgcuuuuuggaugucggcucuuccuaucauaccgaagcagaau
ucgguaagcguuggauuguucacccacuaauagggaacguggaccgucgu
gagacagguuagucccuacugaugaacucgucgcaaugguaauucagcuu
aguacgagaggaaccgcugauucagauaauugguuuuugcgguuguccga
ccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccuc
uaagucagaauccaugccagaacgcgacgauaacccgcacguagacguau
aagaauaggcuccggccucguauccuagcaggcgauuccuccgccggccu
cgaaguggccgucgguaauucgcguauugcaaagacacgcgcgggaucaa
auccuuugcagacgacuuagaugugcgaaaggguccuguaagcaguagag
uagccuuguuguuacgaucugcugaggguaagcccuccuucgccuagauu
uc
........................<<<<<<.....<......>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<<....<<.<<<<<<<<<<.<<.<<<
<<<....>>>>>>>>...>>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<...<<<<.....>>>>...>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<....<....>...
.>>>.>>>.>>....>>>>.>>>>>>>>>.<<.<..<<<<<<<.....>>
>>>>...>..>.>>...<<<<<....<.<<<....>>>.><<<<<<<<<<
....<<.<<<<<<<.....<<<........>>.>.....>>>>>....<<
..<<<<.<......>>>>>.>>.......>>>>..>>>>>>>>.>>..<<
<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<.
..<<<(((.....<<<<<<.....<<..........<<<.<<<<<<<<<<
.......<<<<<.<<<...<<.........>>...>>>.........<<.
.....>>...>>>>>...>>>>>>>>>>>>>..........))).>>...
>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>>>...
.>>>>>.<.<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...
>>>>>>>>>>..>.....>>>>>><<.....<<........<<<<.....
<<<<<<.<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>
>.>>>>>>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<...
.....>>>>>....<<<<<.<<<.....<<<<<<.<<<<<<.<<<<<.<<
<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..........
............>>>>>.>>>>>>>.>>>>>>>>>>...<<<<..>>>>.
....>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>
>....>>>>>.>.>>>>>>.............<<<<<<...<<.......
>>...>>>>>>.....((........<<<<<<..<.<<<<<<<......>
>>>>>>...>.<<<.....))..>>>.....>>>>>..>...<<<<<<..
..>>>.>>>.....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<..
...............>>>>>.><<<<<...<<<<....<<<<<<<<<<..
..>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.........
..>>>>>...>>>>.>>>>....>>>>>>>...<<<<<.<<.......<<
.......<<<<..>>>>....>>........<<<<.....<<<.<<<<<.
......>>>>>.>>>....>>>>..............>>.>>>>>...<<
<<<<<.............>>....<<<<<<<<<.<<<....<<<<....<
<<<<......>>>>>...>>>>...>>>....>>>>..>>>>>...>>>>
>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9v Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H24 T26 R34 P35 S36 R38 K39 G40 A41 Q42 S43 R45 R50 Y62 K85 L86 R91 E98
Binding residue
(residue number reindexed from 1)		H2 T4 R12 P13 S14 R16 K17 G18 A19 Q20 S21 R23 R28 Y40 K63 L64 R69 E76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9v, PDBe:8i9v, PDBj:8i9v
PDBsum8i9v
PubMed37129998
UniProtG0SBN1

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