Structure of PDB 8i9r Chain Li Binding Site BS01

Receptor Information
>8i9r Chain Li (length=88) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHKTTRRVLKERPSRRKGAQSKRTQFVRSLIREVAGLAPYERRVIELLRN
GKDKRARKFSKKKLGTFGRAKRKCEELQRIIAESRRAH
Ligand information
>8i9r Chain C1 (length=2048) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaaggugagag
cuucggcgcaucaucgaccgauccugauguauucggauggauuugaguag
gagcguuaagccuuggacccgaaagauggugaacuaugcuugagcauggg
ggcgaaagacuaaucgaaccaucuaguagcugguuaccgccgaaguuucc
cucaggauagcagugucgaccuucaguuuuaugagguaaagcuuuaaaua
uguaagaagcccuuguuacuuaacugaacgugggcauucgaauguaucga
cacuagugggccauuuuugguaagcagaacuggcgaugcgggaugaaccg
aacgcgggguuaaggugccggaguggacgcucacaaaaggcguuaguaca
ucuuauguacuagcccugggcgcucaagcgucccacccauaccccgcccu
caggguagaaacgaugcccugaggaguaggcggccguggaggucagugac
gaagccuagggcgugagcccgggucgaacggccucuagugcagaucuugg
ugguaguagcaaauacuucaaugagaaggugaacagccucugugauagaa
caauguagauaagggaagucacugucccuaucuacuaucuagcgaaacca
cagccaagggaacgggcuuggcaaaaucagcggggaagacccuguugagc
uugacucuaguuugacauugugaaaagacauaggagguguagaauaggug
ggagcuucggcgccagugaaauaccacuacuccuauuguuuuuuuacuua
uucaaugugaagacauugucagguggggaguuggcggcacaucugugcag
guguccuaaggggggcucauggagaacagaaaucuccaguagaacaaaag
gguaaaaguccccuugauuuugauuuucagugugaauacaaaccaugaaa
guguggccuccuuuagucccucgaaauuugaggcuagaggagaaaaguua
ccacagggaugaccgucgugagacagguuaguucccuacugauacucguc
gcaaugguaauucagcuuaguacgagaggaaccgcugauucagauaauug
guuuuugcgguuguccgaccgggcagugccgcgaagcuaccaucugcugg
auuccaugccagaacgcgacgauaacccgcacgguagacguauaagaaua
ggcuccggccucguauccuagcaggcgauuccuccgccggccucgaagug
gccgucgguaauucgcguauugcaauuuagacacgcgcgggaucaaaucc
uuugcagacgacuuagaugugcgaaaggguccuguaagcaguagaguagc
cuuguuguuacgaucugcugaggguaagcccuccuucgccuagauuuc
.........................<<<<<.....<......>......>
>>>>...........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<<....<<.<<<<<<<<<<.<<.<<<
<<<....>>>>>>>>...>>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<........>>>><<<<<<...<<<<
<<<<<.<<<<..<<<...<<<<.....>>>>...>>>.....<<<<<..<
<....>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>..
..>>>>.>>>>>>>>>.<<.<..<<<<<<<...<<<<<<<..>>>>>.>>
..<<<..(((((.>>>.>>>>>>...>..>.>>...<<<<<......<<<
....>>>..<<<<<<<<<<....<<.<<<<<<<.<.<.........>.>.
>>>>>....<<..<<<<.<......>>>>>.>>.......>>>>..>>>>
>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>
...<<<<<<<...<<<(((.....<<<<<<.......<<<..<<<<<<<<
<...>>>>>>>>>.>>>.)))......>>>>>>.>>>...>>>>>>><<<
<<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<...
...<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>
><<.....<<.......<<<..<<<............>>>..>>><<<<.
....<<<<<<.<<<<<<<<.>>>.>>>>>>>>>>>..>>>>>>....>>.
(..<<<<<......).>>>>>......<<<.<<......<<<<<<.<<<<
<<.<<<<<..<<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<
<......................>>>>>.>>>>>>>.>>>>>>>>>>...
<<<<...>>>>.....>>>>>>>...>>>>>.<<<...<<<<<<<..>>>
>>>>.....<<<<<<<...<<<<<<.......>>>>>>.....<<.....
.>>....>>>>>>>....<<<<.<.<<<.....>>>.>>>>>.<<<....
>>>..>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>>....>>>>>.
>.>>>>>>....<<<<<....>>>.>>.))))).>>..>>>....<<<<<
<<..<<<<...<<<<<.................>>>>>..<<<<<...<<
<<.<<<<<<<<<<<<<....>>>>>..>>>>>>>>>>>>..>>>>>.<<<
<.>>>>.>>>>....>>>>>>>...<<<<<...<<......<<.......
<<<<..>>>>....>>........<<<<.....<<<.<<<<<.......>
>>>>.>>>....>>>>..............>>....>>>>>...<<<<<<
<.............>>....<<<<<<<<<.<<<....<<<<.<..<<<<<
......>>>>>..>>>>>...>>>....>>>>..>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9r Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H24 T26 K32 R34 P35 S36 K39 G40 A41 S43 R45 Q47 R50 Y62 K85 G87 R91 R94 E98
Binding residue
(residue number reindexed from 1)		H2 T4 K10 R12 P13 S14 K17 G18 A19 S21 R23 Q25 R28 Y40 K63 G65 R69 R72 E76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9r, PDBe:8i9r, PDBj:8i9r
PDBsum8i9r
PubMed37129998
UniProtG0SBN1

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