Structure of PDB 8i9z Chain Lh Binding Site BS01

Receptor Information
>8i9z Chain Lh (length=121) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKVKAGQLWSKNKEELTKILGELKTELSQLRIQKISSSGAKLNKIHDLRK
SIARVLTVINAKQRAQLRLFYKNKKYLPLDLRPKLTRALRRRLSKEDASR
VLEKTKKRLTHFPQRKYAVKA
Ligand information
>8i9z Chain C1 (length=2787) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuaugcuuggauagggug
aagccagaggaaacucugguggaggcucgcugacgugcaagaucgucaaa
ucugagcaugggggcgaaagacuaaccaucuaguagcugguuaccgccga
aguuucccucaggauagcagugucgaccuucaguuuuaugagguaaagcg
aaugaacuuuaaauauguaagaagcccuuguuacuuaacugaacgugggc
auucgaauguaucgacacuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacgcgggguuaaggugccggaguggacgcucauc
agacaccacaaaaggcguuaguacaucuugacagcaggacgguggccaug
gaagucggaauccgcuaaggacuguguaacaacucaccugccgaauguac
uagcccugaaaauggauggcgcucaagcgucccacccauaccccgcccuc
aggguagaaacgaugcccugaggaguaggcggccguggaggucagugacg
aagccuagggcgugagcccgggucgaacggccucuagugcagaucuuggu
gguaguagcaaauacuucaaugagaacuugaaggaccgaaguggggaaag
guuccaugugaacagcgguuggacauggguuagucgauccuaagccauag
ggaaguuccguuucaaaggggcacucgugccccguguggcgaaagggaag
ccgguuaauauuccggcaccuggauguggguuuugcgcggcaacgcaacu
gaacgcggagacgacggcgggggccccgggcagaguucucuuuucuucuu
aacggucuaucacccuggaaacaguuugucuggagauaggguuuaauggc
cggaagagcccgacacuucugucggguccggugcgcucucgacgucccuu
gaaaauccgcgggagggaauaauucucacgccaggucguacucauaaccg
cagcagguccccaaggugaacagccucugguugauagaacaauguagaua
agggaagucggcuccguaacuucgggaaaagggcucuaaggguugggcac
guugggcuuugggcggacgcccugggagcagagggccucuagccgggcaa
ccggccggcggcccucagcacccgggguugaagcccuuagcccggcgugc
gguuaacaaccaacuuagaacugguacggacacacugucccuaucuacua
ucuagcgaaaccacagccaagggaacgggcuuggcaaaaucagcggggaa
agaagacccuguugagcuugacucuaguuugacauugugaaaagacauag
gagguguagaauaggugggagcuucggcgccagugaaauaccacuacucc
uauuguuuuuuuacuuauucaaugugaagacauugucagguggggaguuc
cuuuagucccucgaaauuugaggcuagaggagaaaaguuaccacagggau
aacuggcuuguggcggccaagcguucauagcgacgucgcugaugucggcu
cuuccuaucauaccgaagcagaauucgguaagcguuggauuguucaccca
cuaauagggagugagcuggaccgucgugagacagguuagucccuacugau
gaacucgucgcaaugguaauucagcuuaguacgagaggaaccgcugauuc
agauaauugguuuuugcgguuguccgaccgggcagugccgcgaagcuacc
aucugcuggauaauggcugaacgccucuaagucagaauccaugccagaac
gcgacgauacuacccgcacguuguagacguauaagaauaggcuccggccu
cguauccuagcaggcgauuccuccgccggccucgaaguggccgucgguaa
uucgcguauugcaauuuagacacgcgcgggaucaaauccuuugcagacga
cuuagaugugcgaaaggguccuguaagcaguagaguagccuuguuguuac
gaucugcugaggguaagcccuccuucgccuagauuuc
........................<<<<<<.....<......>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<....<<<
<<<<<.<<<<..<<<...<<<<.....>>>>...>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<<.
..<<<<<<<....>>>>>>>...>.>>>..<<<<<........>>>>>..
>>>>>>>>>..<<.<....>.>>.>>>>>>>.....>.>>...<<<<<..
..<.<<<....>>>.><<<<<<<<<<....<<.<<<<<<<.....<<<..
......>>.>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<...<<<(((.....<<<<<<.....
.<..........<<<.<<<<<<<<<<.....<.<<<<<.<<<...<<...
......>>...>>>.........<<......>>...>>>>>.>.>>>>>>
>>>>>>>..........))).>....>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<
...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<
<<....>>>........<<<<<......>>>>>....>>>....>>...<
<<<<........>>>>>))<<<<.<<<<.<<<....<<<....>>>....
...<<<<<<...<<<<.<<<<<<<<<<<<<.<<<<...((..>>>>.><.
..<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>
>>....><<<<<<<<....>>>>>>>>>>>>.>.>>>>>>>.>>>>....
.....>>>>>>.........>>>...>>>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<
.<<.......<.<<<<<<.<.<<.................<<<<<.<<<<
<..<.<<<..<<<<....<<<<<<<<.<<.<<<<<<<.<<.<<<<<....
>>>>>.>>.>>>>>>>.>>.>>>>>>>>....>>>>..>>>>...>>>>>
......>>>>>......>>...>.>>>>>>....>...>>.>>>>>>>..
>>>>>>....>>....<<<<<........>>>>>....<<<<<..<<<..
......<<<<<<.<<<<<<.<<<<<.<<<<<<<<..<<<<<<<<<<<<<<
<<<..........<<<<<......................>>>>>.>>>>
>>>.>>>>>>>>>>...<<<<...>>>>.....>>>>>>>>..>>>>>..
<<<<<<..<<<<<<...>>>>>>>>>>>>.....>>>>>.>.>>>>>>..
.((........<<<<<<...<<.......>>...>>>>>>((....<<<<
.<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.<...))>.>>>
.....>>>>>)).>>>>.<<<<<<<....>>>.>>>>....>>>.>>>>>
....<<<<<<<..<<<<.<.<<<<<.................>>>>>.><
<<<<...<<<<....<<<<<<<<<<))..>>>>>..>>>>>...>>>>..
>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>....
>>>>>>>.....<<<<<.<<.<<<......<<.......<<<....>>>.
...>>........<<<<.....<<<.<<<<<.......>>>>>.>>>...
.>>>>..............>>>>>.>>>>>...<<<<<<<..........
...>>....<<<<<<<<<.<<<....<<<<.<..<<<<<......>>>>>
..>>>>>...>>>....>>>>..>>>>>...>>>>>.
Receptor-Ligand Complex Structure
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PDB8i9z Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		K79 Y80 R86 R91 R95 E107 K108 K111 H115 F116
Binding residue
(residue number reindexed from 1)		K75 Y76 R82 R87 R91 E103 K104 K107 H111 F112
Enzymatic activity
Enzyme Commision number 2.4.99.18: dolichyl-diphosphooligosaccharide--protein glycotransferase.
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0004576 oligosaccharyl transferase activity
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006486 protein glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
Cellular Component
GO:0005840 ribosome
GO:0016020 membrane
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9z, PDBe:8i9z, PDBj:8i9z
PDBsum8i9z
PubMed37129998
UniProtG0S0D7

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