Structure of PDB 8rxx Chain Lf Binding Site BS01 |
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| >8rxx Chain L1 (length=1657)
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agaccugaguguggcaggacuacccgccgaacuuaagcauauuacucagc
ggaggaaaagaaaacaaccgugauucucucagugagcggcgagcgaagag
ggaacgaacucguugccgaaucgggucuuacaaggccuugaguuguggca
caaauaucauugugugguuggugcaggaguggcgaaauucaagcgaaaag
caaacccguugcugaauacaacccuucaugugaguauugagccaaagaag
guguuagcccauugagccauaaaccugagcgccucaugaacaagcgagua
gcacuguuugggaaugcagugucaaguuggcagguauuugucugccaaag
uuaaauacagaguaggaagaccgauagcgaacaaguagcgugagcgaaag
uuugaaaagcacuuuggaaagagagugaaauagaaccugaagucgugaca
aagacaauggaaguaccuccauuucaacggccagaaccagcccuacugca
uuauccugucggggaucaaaauccggcgggcaacgaagugcaagaaucuu
gggucuuggugaaaugagcggaguauuugagcugcgcacggcggccgcac
gcacugguuucuucuccgugaugcuccauguuggcgauggaaauggggug
cccccacccgucuugaaacacggaccaaggagucaaacagacgcgcaagg
gaggagauaugguugccaguacuucucucguacugaaagggagaugcaaa
augcaucuguggugugcacacgucaaauccguuugauuugcccaacaccg
accggcccuccguggguugcguuggagugugccuguuuggacccgaaagg
uggugaacuaugccugaacaaggugaagcccggggaaacccagguggagg
ccuguagcgaugcugacgugcaaaucgcucguaugauuuggguaucggag
cgaaagacucaucgaaccaccuaguagcugguucacaucgaaguuucccu
caggauagcuggugcuaguagaaguauugugcgguaaagcaaaugauuag
agggaccuauucucaaacuuuaaaugugcaaacaaaccgugccuuagcca
acugcaaggccggaaagaaaagaauuagaggcaccaagugggccuucuuc
gguaagcggagcaggcgaugcggaaugaaccgcuuagggauauguggcgu
caaaacuuaugggcucauucucgauacgugaaaaggguguugguggauaa
auccaccggccccgaaaauggaugacgcuuaagcccaauuagugauugcc
cauuauuccuuugguaagggcggaaacaaauggagaaaguguagcccuuc
cgauguagauguggccuggagguuaggacgaagcuuauggcgugagccua
agauggaccggccucuagugcagaucuugguuggcguagcaaagaucuaa
cggagauauacucaacaugcaacguuggauacuggagcggggaaggauuu
cgugccaacggcacucguacacgaguuguucggaaacugagcacaacguu
auaucguuuuguuaggaaagugaaggugugucggcggagcuguucgacug
ugaaaaggggcaacagagaaccugggauuauauuccaaaaagaaauugca
uguggga |
......................<<<<<......<......>.......>>
>>.>.........<<....>>..<<<<<<......<<.....>>....>>
>>>>...<<<...<<<<<..<<<<<<<......>>>>>.>>....>>>>>
............<<<<...<<<<<<<<.<<<<<......<<<......<<
<<.......>>>>.....<<........>>......>>>.<<.......(
(.....>>)).....>>>>>...>>>..>>>>>.>>>>............
<<<<<<<........>>>>>>>......<<<<<........>>>>>..>>
>....................................<<....>>.....
...........<<<<....>>>>...........................
.......<<<..<<<<<<.<<<<<...<<.<<<<.<<<<<<<<....<<<
<<..<<<<<<<<<........>>>>>>>>>.....>>.>>>.........
>>>>..>>>>........<<<<<.....<<<<<<.<<.<<<<.>>>>...
>>.>.>>>.>>..>>>>>.....<<<<...>>>>>>....>>>>>>>>>>
>..>>>.<<<<........>>>><<<<<<...<<<<<<<<.<<<<<..<<
<..<<<.<............>>>>..>>>...<<....>>..<<<<<...
..>>>>>...<<<<<...<<.<<<<<<....>>>>>>.>>....>>>>><
<<<<<<<<.....>>>>>>.>>>...>>>>>.>>>>>>>>.<<.<...<<
<<<<.....<<<<<<<<<..<<<....<<<.<<<....>>>.>>>.....
>>>...<<<<.<<.<<........>>>>>>>>....>>>>>>>>>...<<
.......>>......>>>>>>......>.>>...<<<<<....<.<<<..
..>>>.><<<<<<<<<.....<<...<<<<<<<...<<<....<<...<.
<<<..>>>.>...>>..>>.>...>>>>>>>.....<<<.<<<<<.<<..
...>>>>>>>>>>...........>>...>>>>>>>.>>..<<<<.<<<<
<.....>>>>>.>>>>...<<<<......>>>>..<<<<<<<...<<<((
(......<..<<<<........<...........<<<.<<<<<<<<<<..
>>>>>>>>>>>>>..........))).>....>>>>.>.........>>>
...>>>>>>><<<<.<<<<<...........>>>>.........>>>>>>
>>>....>>>>>....<<<<<<<<.........<<<..<<<....>>>.>
>>.......>>>>>>>>........>>>>>>..............<<<<<
<<....................>>>>>>>....................<
<<<<....<<.....>>..>>>>>....<<..........<<.<<<<<..
....>>>>............<.......<<...<......>...>>....
.>.....>.>>..........<<<<.........>>....>>.>>.....
....... |
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| PDB | 8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. |
| Resolution | 2.97 Å |
Binding residue
(original residue number in PDB) | K3 P4 V6 K12 K13 K16 R17 F18 R22 E24 F26 P27 Q28 L29 S32 W33 R34 K35 R37 E39 D40 S41 P42 R44 R45 R46 Y47 K48 G49 K51 P54 N55 K56 G57 Y58 G59 S60 D61 R62 K65 Y66 P69 S70 N78 N79 Y84 M88 V96 S98 H99 T100 G102 A103 R104 K105 R106 K107 R111 K112 R119 N122 |
Binding residue
(residue number reindexed from 1) | K2 P3 V5 K11 K12 K15 R16 F17 R21 E23 F25 P26 Q27 L28 S31 W32 R33 K34 R36 E38 D39 S40 P41 R43 R44 R45 Y46 K47 G48 K50 P53 N54 K55 G56 Y57 G58 S59 D60 R61 K64 Y65 P68 S69 N77 N78 Y83 M87 V95 S97 H98 T99 G101 A102 R103 K104 R105 K106 R110 K111 R118 N121 |
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| Enzyme Commision number |
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