Structure of PDB 8pv2 Chain Lc Binding Site BS01

Receptor Information
>8pv2 Chain Lc (length=95) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIGAKLALVIKSGKVVLGYRSTLKALRSGKAKLILIAANTPPLRKSELEY
YSMMSKTPVHHYSGTNIELGTACGKLFRCSTMAILDAGDSDILAD
Ligand information
>8pv2 Chain C1 (length=3056) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacuau
gcuuggauagggugaagccagaggaaacucugguggaggcucgcagcggu
ucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacuaa
ucgaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcag
ugucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaa
gaagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacua
gugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgc
gggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguua
guacaucuugacagcaggacgguggccauggaagucggaauccgcuaagg
acuguguaacaacucaccugccgaauguacuagcccugaaaauggauggc
gcucaagcgucccacccauaccccgcccucaggguagaaacgaugcccug
aggaguaggcggccguggaggucagugacgaagccuagggcgugagcccg
ggucgaacggccucuagugcagaucuuggugguaguagcaaauacuucaa
ugagaacuugaaggaccgaaguggggaaagguuccaugugaacagcgguu
ggacauggguuagucgauccuaagccauagggaaguuccguuucaaaggg
gcaugccccguguggcgaaagggaagccgguuaauauuccggcaccugga
uguggguuuugcgcggcaacgcaacugaacgcggagacgacggcgggggc
cccgggcagaguucucuuuucuucuuaacggucuaucacccuggaaacag
uuugucuggagauaggguuuaauggccggaagagcccgacacuucugucg
gguccggugcgcucucgacgucccuugaaaauccgcgggagggaauaauu
cucacgccaggucguacucauaaccgcagcagguccccaaggugaacagc
cucugguugauagaacaauguagauaagggaagucggcaaaauagauccg
uaacuucgggaaaaggauuggcucuaaggguugguaacaaccaacuuaga
acugguacggacagggggaaucugacugucuaauuaaaacauagcauugc
gauggccagaaagugguguugacgcaaugugauuucugcccagugcucug
aaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggaguaa
cuaugacucucuguagccaaauggauuaacgagauucccacugucccuau
cuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaaucagc
ggggaaagaagacccuguugagcuugacucuaguuugacauugugaaaag
auuuuuuuacuuauucaaugaagcggggcuggacuugcguccaacuucug
gaguuaagguccuucgcgggccgacccggguugaagacauugucaggugg
ggaguuuggcuggggcggcacaucugugcagguguccuaaggggggcuca
uggagaacagaaaucuccaguagaacaaaaggguaaaaguccccuugauu
uugauuuucagugugaauacaaaccaugaaaguguggccuaucgauccuu
uagucccucgaaauuugaggcuagaggugccagaaaaguuaccacaggga
uggcuuguggcggccaagcguucauagcgacgucgcuuugauccuucgau
gucggcucuuccuaucauaccgaagcagaauucgguaagcguuggauugu
ucacccacuaauagggaacgugagcuggguuuagaccgucgugagacagg
uuaguuuuacccuacugaugaacucgucgcaaugguaauucagcuuagua
cgagaggaaccgcugauucagauaauugguuuuugcgguuguccgaccgg
gcagugccgcgaagcuaccaucugcuggauaauggcugaacgccucuaag
ucagaauccaugccagaacgcgacgauacuacccgcacguuguagacgua
uaagaauaggcuccggccucguauccuagcaggcgauuccuccgccggcc
ucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgcggga
ucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaagcagu
agaguagccuuguuguuacgaucugcugaggguaagcccuccuucgccua
gauuuc
........................<<<<<<.....<...<..>......>
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>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<<...<<<<......>>>>.((..
....<<<.....))>>>.>..>>..>>.>>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<..(((((
(>>>>>..>>>....].............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<...<<....>>..
.>>>>.>>.>>....>>>>.>>>>>>>>>.<<.<...<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.
<<.<<........>>>>>>>>....>>>>>>>>>...<<.......>>..
....>>>>>>......>.>>...<<<<<......<<<....>>>..<<<<
<<<<<.....<<.<<<<<<<.....<<<........>>.>.....>>>>>
...<<<<.<<<<.<......>>>>>.>>>>.....>>>>...>>>>>>>.
>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<
<<<<<...<<<(((.....<<<<<<......<..........<<<.<<<<
<<<<<<.......<<<<<.<<<...<<.........>>...>>>......
...<<......>>...>>>>>...>>>>>>>>>>>>>..........)))
.>....>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>
>>>....>>>>>.<.<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<
.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.....>
>.>>>>>>....((<<<<<<...<<<<..<<<....>>>........<<<
<<..>>>>>...>>>>....>>...<<<<<........>>>>>))<<<<.
<<<<.<<<....<<<....>>>.....((<<<<<<...<<<<.<<<<<<<
.<<<<<.<<<<...[[..>>>>.><...<<<<<....<<<<<<....<<<
.....>>>....>>>>>>.....>>>>>....><<<<<<<......>>>>
>>>>>>>...>>>>>>>.>>>>.........>>>>>>.........>>>.
..>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>
>>..>>>>..<<<<.....<<<<<<<.<<.........<.....<<<<<.
....<..>......>>>>><<.<<<<<<<<<<<....>>>>>..>>>>>>
.>>............<<<<<<<<<..<<<.........>>>..<<<<<<<
....<<<<.....>>>>......>>>>>>>.........<<.<<<<<<..
..<<<.....<<<<....>>>>.....>>>.>>>>..>>>>.<<<<<<..
.....>>>>>>......<<..>>......>>.>>>>>>>..>..>>.>>>
>>>>..>>>>>>....>>....<<<<<........>>>>>....<<<<<.
.<<<........<<<<<.<<<<<<..<<<<<.<<<<<<<<..<<<<<<<<
..>>>>>>>>...<<<<<.....<<<<..<<<<<....>>>>>.......
...))..<<<<<.....>>>>>..>>>>..>>>>>.....>>>>>>>>..
>>>>>.......<<<<<<.<<<<<<....>>>>>>>>...<<<<<<<...
<<<<<<.......>>>>>>.....<<......>>....>>>>>>>....<
<<<.<.<<<.....>>>.>>>>><<<<....>>>.>>>>>.<<...<<<<
<<<..<<<<.))))))>>>>>>>>>>>.....>>..>>>>..>>>>>>>.
........<<<<<<...<<.......>>...>>>>>>.............
..<<<<...<<<<..<.<<<<<<<......>>>>>>>...>.<<<.....
....>>>.....>>>>.......>>>>......<<<<<<<....>>>.>>
>>........>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<......
...........>>>>>.><<<<<...<<<<....<<<<<<<<<<]]..>>
>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>
>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<......<
<.......<<<....>>>....>>........<<<<.....<<<.<<<<<
.......>>>>>.>>>....>>>>..............>>>>>.>>>>>.
..<<<<<<<.............>>....<<<<<<<<<.<<<....<<<<.
<..<<<<<......>>>>>..>>>>>...>>>....>>>>..>>>>>...
>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv2 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.63 Å
Binding residue
(original residue number in PDB)		L28 G29 Y30 R31 S32 K35 P52 P53 R55 S57 L87 F88 R89 C90 S91
Binding residue
(residue number reindexed from 1)		L17 G18 Y19 R20 S21 K24 P41 P42 R44 S46 L76 F77 R78 C79 S80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8pv2, PDBe:8pv2, PDBj:8pv2
PDBsum8pv2
PubMed37921038
UniProtG0SEI0

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