Structure of PDB 8fl9 Chain LZ Binding Site BS01

Receptor Information
>8fl9 Chain LZ (length=50) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
Ligand information
>8fl9 Chain L1 (length=154) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
cgcu
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<<...>>>>>>>>>................
....
Receptor-Ligand Complex Structure
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PDB8fl9 Principles of human pre-60 S biogenesis.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R8 K15 K18 Q19 R21 P24 W26 M29 K30 T31 I35 K40
Binding residue
(residue number reindexed from 1)		R7 K14 K17 Q18 R20 P23 W25 M28 K29 T30 I34 K39
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0002227 innate immune response in mucosa
GO:0006412 translation
GO:0019731 antibacterial humoral response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fl9, PDBe:8fl9, PDBj:8fl9
PDBsum8fl9
PubMed37410842
UniProtP62891|RL39_HUMAN Large ribosomal subunit protein eL39 (Gene Name=RPL39)

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