Structure of PDB 7mqa Chain LZ Binding Site BS01

Receptor Information
>7mqa Chain LZ (length=162) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRKLKFHEQKLLKQVDFLNWEREDYTRYNQLSRAVRELARRLRDLPERDQ
FRVRASAALLDKLYALGLVPTRGSLELCDFVTASSFCRRRLPTVLLKLRM
AQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHV
LEYNEERDDFDL
Ligand information
>7mqa Chain L2 (length=177) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauaguguguuacuaaaccacgaggaagagag
guagcguuuucuccugagcgugaagccggcuuucuggcguugcuuggcug
caacugccgucagccauugaugaucguucuucucuccguauuggggagug
agagggagagaacgcggucugaguggu
..................................<<<<<.....<<....
...<<<<<<<<<<<<....<.......<<<<....<<<<<<<<......>
>>>>.>>>...>>>>.........>..<<<<<<<<<<.....>>>>>>.>
>>>>>>>>>>>>>>>...>>..>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7mqa Nucleolar maturation of the human small subunit processome.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		F7 H8
Binding residue
(residue number reindexed from 1)		F6 H7
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0030515 snoRNA binding
Biological Process
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030684 preribosome
GO:0032040 small-subunit processome
GO:0034457 Mpp10 complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtQ9NV31|IMP3_HUMAN U3 small nucleolar ribonucleoprotein protein IMP3 (Gene Name=IMP3)

[Back to BioLiP]