Structure of PDB 9fq0 Chain LX Binding Site BS01

Receptor Information

>9fq0 Chain LX (length=116) Species: 9606 (Homo sapiens)

RTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKI
EDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRL
APDYDALDVANKIGII

Ligand information

>9fq0 Chain 8 (length=58)

aacgcagcuagcugcgagaauuaaugugaauugcaggacacauugaucau
cgacacuu

<<<<<<<<....>>>>.....<.<<<......>>.............>>>
..>...>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 9fq0 Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome
• Resolution: 4.67 Å
• Binding residue (original residue number in PDB): R68 K70
• Binding residue (residue number reindexed from 1): R28 K30

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0045296 cadherin binding
• GO:1904841 TORC2 complex binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:0070062 extracellular exosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:9fq0, PDBe:9fq0, PDBj:9fq0
• PDBsum: 9fq0
• UniProt: P62750|RL23A_HUMAN Large ribosomal subunit protein uL23 (Gene Name=RPL23A)