Structure of PDB 8rxh Chain LX Binding Site BS01

Receptor Information
>8rxh Chain LX (length=85) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRTIECEFSHFAVHPGHGRRYVPFAFLSTKPVLTFSRPKCFALYMRKKNP
RFIPWTRTYRRIHRRVQRAIVGADLSYIQEVRAAR
Ligand information
>8rxh Chain L4 (length=184) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugggauugugaagggaucucgcagguaucgugagggaaguaugggguag
uacgagaggaacucccaugccgugccucuaguuucugggguuugucgaac
ggcaagugccccgaagccaucgcacggugguucucggcugaacgccucua
agccagaagccaaucccaagaccagaugcccacu
<<<<<<<.........>>>>>>>.<<<<<<....<<<<.<<<<<<<<...
............>>>>>>>><<<<<...<.<<....<<<<<<<<<.....
.>>>>..>>>>>...>>.>..>>>>>.<<<<....<<<<...........
>>>>....>>>>.>>>>.......>>>>>>....
Receptor-Ligand Complex Structure
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PDB8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.93 Å
Binding residue
(original residue number in PDB)		G16 G18 R19 P38 R46
Binding residue
(residue number reindexed from 1)		G16 G18 R19 P38 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxh, PDBe:8rxh, PDBj:8rxh
PDBsum8rxh
PubMed38722744
UniProtQ4Q1W6

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