Structure of PDB 7mq9 Chain LW Binding Site BS01

Receptor Information
>7mq9 Chain LW (length=453) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QDPFPGPAPVPVEVVQKFCRIDKSRKLPHSKAKTRSRLEVAEAEEEETSI
KAARSELLLAEEPGFLEGEDGEDTAKICQADIVEAVDIASAAKHFDLNLR
QFGPYRLNYSRTGRHLAFGGRRGHVAALDWVTKKLMCEINVMEAVRDIRF
LHSEALLAVAQNRWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATAS
ETGFLTYLDVSVGKIVAALNARAGRLDVMSQNPYNAVIHLGHSNGTVSLW
SPAMKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRGTYQP
LSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAGQGKASPPSLEQPYLTH
RLSGPVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSR
KQRQEWEVKALLEKVPAELICLDPRALAEVDVISLEQGKKEQIERLSALD
RFV
Ligand information
>7mq9 Chain L0 (length=242) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucgauguggugacgucgugcucucccgggccggguccgcggaccccgg
cccgaccucgcgcgggguccucugacgcggcagacagcccucgcugucgc
cgacuugcgggcggccccccuccgcggcggugggggugccgucccgccgg
cccgugcgucggcuccgggcccuugcggugcuccuggagcgcuccggguu
gcaggugcccgaggccgaugagaaaagccuucucuagcgauc
...................<<.<<....<<<<<<<<<<<<>>>>>>>.>>
>>><<<<<<<..>>>>>>>....>>>>.<<<<<......>>.>>><<<<.
>>>>...<<<<<<<<<<<<<.<<<...>>>.>>>>>.>>>>>.>>>..<<
<<<<..>>..>>>>....................................
...............<<.>>......................
Receptor-Ligand Complex Structure
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PDB7mq9 Nucleolar maturation of the human small subunit processome.
Resolution3.87 Å
Binding residue
(original residue number in PDB)		R194 R216 Q265 R274 F298 R316 N338 T340 R359 D380 H381 D421 R494 Q498
Binding residue
(residue number reindexed from 1)		R100 R122 Q171 R180 F204 R222 N244 T246 R265 D286 H287 D327 R400 Q404
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mq9, PDBe:7mq9, PDBj:7mq9
PDBsum7mq9
PubMed34516797
UniProtO15213|WDR46_HUMAN WD repeat-containing protein 46 (Gene Name=WDR46)

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