Structure of PDB 8i9t Chain LV Binding Site BS01

Receptor Information
>8i9t Chain LV (length=135) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRGAPGGKLKMTLGLPVGAIMNCADNSGARNLYIIAVKGAGARLNRLPAG
GVGDMVMATVKKGKPELRKKVHPAVIVRQAKPWKRFDGVFLYFEDNAGVI
VNPKGEMKGSAITGPVGKEAAELWPRIASNAGVVM
Ligand information
>8i9t Chain C1 (length=2132) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacaac
caucuaguagcugguuaccgccgaaguuucccucaggauagcagugucga
ccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaagaagcc
cuuguuacuuaacugaacgugggcauucgaauguaucgacacuagugggc
cauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcgggguu
aaggugccggaguggacgcucaucagacaccacaaaaggcguuaguacau
cuugacagcaggacgguggccauggaagucggaauccgcuaaggacugug
uaacaacucaccugccgaauguacuagcccugaaaauggauggcgcucaa
gcgucccacccauaccccgcccucaggguagaaacgaugcccugaggagu
aggcggccguggaggucagugacgaagccuagggcgugagcccgggucga
acggccucuagugcagaucuuggugguaguagcaaauuugauagaacaau
guagauaagggaagucggcgggaaucugcgagauucccacugucccuauc
uacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaaucagcg
gggaagacccuguugagcuugacucuaguuugacauugugaaaagacaua
ggagguguagaauaggugggagcuucggcgccagugaaauaccacuacuc
cuauuguuuuuuuacuuauucaaugugaagacauugucagguggggaguu
ccuuuagucccucgaaauuugaggcuagaggagaaaaguuaccacaggga
uaacuggcuuguggcggccaagcguucauagcgacgucgcuuuuuggaug
ucggcucuuccuaucauaccgaagcagaauucgguaagcguuggauuguu
cacccacuaauagggaacguggaccgucgugagacagguuagucccuacu
gaugaacucgucgcaaugguaauucagcuuaguacgagaggaaccgcuga
uucagauaauugguuuuugcgguuguccgaccgggcagugccgcgaagcu
accaucugcuggauaauggcugaacgccucuaagucagaauccaugccag
aacgcgacgauaacccgcacguagacguauaagaauaggcuccggccucg
uauccuagcaggcgauuccuccgccggccucgaaguggccgucgguaauu
cgcguauugcaaagacacgcgcgggaucaaauccuuugcagacgacuuag
augugcgaaaggguccuguaagcaguagaguagccuuguuguuacgaucu
gcugaggguaagcccuccuucgccuagauuuc
........................<<<<<<.....<......>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<<....<<.<<<<<<<<<<.<<.<<<
<<<....>>>>>>>>...>>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.....<.<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>....>.>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<...<<<<.....>>>>...>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<....<....>...
.>>>.>>>.>>....>>>>.>>>>>>>>>.<<.<..<<<<<<<.....>>
>>>>...>..>.>>...<<<<<....<.<<<....>>>.><<<<<<<<<<
....<<.<<<<<<<.....<<<........>>.>.....>>>>>....<<
..<<<<.<......>>>>>.>>.......>>>>..>>>>>>>>.>>..<<
<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<.
..<<<(((.....<<<<<<.....<<..........<<<.<<<<<<<<<<
.......<<<<<.<<<...<<.........>>...>>>.........<<.
.....>>...>>>>>...>>>>>>>>>>>>>..........))).>>...
>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>>>...
.>>>>>.<.<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...
>>>>>>>>>>..>.....>>>>>><<.....<.........<<<<.....
<<<<<<.<<<<<<<<....<<<<<<<<<>>.>>>>>>>>>>.>>>>>>>>
>>>..>>>>.>....>>....<<<<<........>>>>>....<<<<<.<
<<.....<<<<<<.<<<<<<.<<<<<..<<<<<<<..<<<<<<<<<<<<<
<<<<..........<<<<<......................>>>>>.>>>
>>>>.>>>>>>>>>>...<<<<...>>>>.....>>>>>>>...>>>>>.
<<<<<<<..<<<<<<...>>>>>>>>>>>>>....>>>>>.>.>>>>>>.
............<<<<<<...<<.......>>...>>>>>>.....((..
......<<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.....)
)..>>>.....>>>>>..>..<<<<<<<....>>>.>>>>....>>>.>>
>>>....<<<<<<<..<<<<.<.<<<<<.................>>>>>
.><<<<<...<<<<...<<<<<<<<<<<....>>>>>..>>>>>>..>>>
>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>.
...>>>>>>>...<<<<<.<<.......<<.......<<<....>>>...
.>>........<<<<.....<<<.<<<<<.......>>>>>.>>>....>
>>>..............>>.>>>>>...<<<<<<<.............>>
....<<<<<<<<<.<<<....<<<<.<..<<<<<......>>>>>..>>>
>>...>>>....>>>>..>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9t Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R6 K12 K14 T16 R34 Y37 K42 R47 L48 K65 K66 G67 F94
Binding residue
(residue number reindexed from 1)		R2 K8 K10 T12 R30 Y33 K38 R43 L44 K61 K62 G63 F90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9t, PDBe:8i9t, PDBj:8i9t
PDBsum8i9t
PubMed37129998
UniProtG0SI44

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