Structure of PDB 7mq8 Chain LT Binding Site BS01

Receptor Information
>7mq8 Chain LT (length=869) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTASALFAGFRALGLFSNDIPHVVRFSALKRRFYVTTCVGKSFHTYDVQK
LSLVAVSNSVPQDICCMAADGRLVFAAYGNVFSAFARNKEIVHTFKGHKA
EIHFLQPFGDHIISVDTDGILIIWHIYSEEEYLQLTFDKSVFKISAILHP
STYLNKILLGSEQGSLQLWNVKSNKLLYTFPGWKVGVTALQQAPAVDVVA
IGLMSGQVIIHNIKFNETLMKFRQDWGPITSISFRTDGHPVMAAGSPCGH
IGLWDLEDKKLINQMRNAHSTAIAGLTFLHREPLLVTNGADNALRIWIFD
GPTGEGRLLRFRMGHSAPLTNIRYYGQNGQQILSASQDGTLQSFSTVHEK
FNKSLGHGLINKKRVKRKGLQNTMSVRLPPITKFAAEEARESDWDGIIAC
HQGKLSCSTWNYQKSTIGAYFLKPKELKKDDITATAVDITSCGNFAVIGL
SSGTVDVYNMQSGIHRGSFGKDQAHKGSVRGVAVDGLNQLTVTTGSEGLL
KFWNFKNKILIHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRK
IVREFSGHQGQINDMAFSPDGRWLISAAMDCSIRTWDLPSGCLIDCFLLD
SAPLNVSMSPTGDFLATSHVDHLGIYLWSNISLYSVVSLRPLPADYVPSI
VMLPGTCQSDELIEYDSPEQLNEQLVTLSLLPESRWKNLLNLDVIKKKNK
PKEPPKVPKSAPFFIPTIPGLVPRYAAPEQPQQSKVVNLGVLAQKSDFCL
KLEEGLVNNKYDTALNLLKESGPSGIETELRSLSPDCGGSIEVMQSFLKM
IGMMLDRKRDFELAQAYLALFLKLHLKMLPSEPVLLEEITNLSSQVEENW
THLQSLFNQSMCILNYLKS
Ligand information
>7mq8 Chain L0 (length=242) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucgauguggugacgucgugcucucccgggccggguccgcggaccccgg
cccgaccucgcgcgggguccucugacgcggcagacagcccucgcugucgc
cgacuugcgggcggccccccuccgcggcggugggggugccgucccgccgg
cccgugcgucggcuccgggcccuugcggugcuccuggagcgcuccggguu
gcaggugcccgaggccgaugagaaaagccuucucuagcgauc
...................<<.<<....<<<<<<<<<<<<>>>>>>>.>>
>>><<<<<<<..>>>>>>>....>>>>.<<<<<......>>.>>><<<<.
>>>>...<<<<<<<<<<<<<.<<<...>>>.>>>>>.>>>>>.>>>..<<
<<<<..>>..>>>>....................................
...............<<.>>......................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7mq8 Nucleolar maturation of the human small subunit processome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		A91 L92 K93 K113 S115 L136 A149 R150 L372 R375 E412 K413 N424 K426 R427 R430 K431 S438 K467 L468 S469 F484 K486 K491 D493
Binding residue
(residue number reindexed from 1)		A28 L29 K30 K50 S52 L73 A86 R87 L309 R312 E349 K350 N361 K363 R364 R367 K368 S375 K404 L405 S406 F421 K423 K428 D430
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006364 rRNA processing
GO:0007601 visual perception
GO:0008150 biological_process
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ8NI36|WDR36_HUMAN WD repeat-containing protein 36 (Gene Name=WDR36)

[Back to BioLiP]