Structure of PDB 5wlc Chain LT Binding Site BS01

Receptor Information
>5wlc Chain LT (length=850) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNSKIFSPFRIIGNVSNGVPFATGTLGSTFYIVTCVGKTFQIYDANTLHL
LFVSEKETPSSIVALSAHFHYVYAAYENKVGIYKRGIEEHLLELETDANV
EHLCIFGDYLCASTDDNSIFIYKKSDPQDKYPSEFYTKLTVTEIQGGEIV
SLQHLATYLNKLTVVTKSNVLLFNVRTGKLVFTSNEFPDQITTAEPAPVL
DIIALGTVTGEVIMFNMRKGKRIRTIKIPQSRISSLSFRTDGSSHLSVGT
SSGDLIFYDLDRRSRIHVLKNIHRESYGGVTQATFLNGQPIIVTSGGDNS
LKEYVFDPSLSQGSGDVVVQPPRYLRSRGGHSQPPSYIAFADSQSHFMLS
ASKDRSLWSFSLRKDAQSQEMSQRLHKKQDGGRVGGSTIKSKFPEIVALA
IENARIGEWENIITAHKDEKFARTWDMRNKRVGRWTFDTTDDGFVKSVAM
SQCGNFGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMV
SCGLDGIVGFYDFNKSTLLGKLKLDAPITAMVYHRSSDLFALALDDLSIV
VIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWDLPTGG
CIDGIIVDNVATNVKFSPNGDLLATTHVTGNGICIWTNRAQFKTVSTRTI
DESEFLNDIDFNTYTSLEQIDKELLTLSIGPRSKMNTLLHLDVIRKRSKP
KEAPKKSEKLPFFLQLSGEKRLGFESHFTKQLREGSQSKDYSSLLATLIN
FSPAAVDLEIRSLNSFEPFDEIVWFIDALTQGLKSNKNFELYETFMSLLF
KAHGDVIHANNKNQDIASALQNWEDVHKKEDRLDDLVKFCMGVAAFVTTA
Ligand information
>5wlc Chain L0 (length=488) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagacaagugcuugucguucguuaauggccucgucaaacgguggagaga
gucgcuaggugaucgucagaucugccuagucucuauacagcguguuuaau
ugacauggguugaugcguauugagagauacaauuugggaagaaauuccca
gaguguguuucuuuugcguuuaaccugaacagucucaucgugggcaucuu
gcgauuccauuggugagcagcgaaggauuugguggauuacuagcuaauag
caaucuauuucaaagaauucaaacuugggggaaugccuuguugaauauuc
uucaaguguaaccuccucucaaaucagcgauaucaaacguaccccgugaa
acaccgggguaucuguuugguggaaccugauuagaggaaacucaaagagu
gcuaugguauggugacggagugcgcuggucaagaguguaaaagcuuuuug
aacagagagcauuuccggcagcagagauuucagcuguu
<<<<<<<<<..>>>>>>.>>>............<<<<<<<<.<<...<<<
<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>...>>.>>>......>
>>>>..<<<<<<..<<<<<..<<<<<<<<<<.<<<<<<<<....>>>>>>
>>.>>>>>>>>>>.>>>>>.>>>>>>.......<<<<<<<<<<<......
.....>>>>>.>>>>>>.........................<<<...>>
>.........................<<<<<..<<<<<<<..<<<..>>>
..>>>>.>>.>>>>>>.....<<<<<<...<<<<<<<<<<<<<<<<....
....>>>>>>>.>.>>>>>>>>....>>>>>>..................
...............<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>
>.>>>...>>>>.>>>><<<<<.<<<..>>>.>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wlc The complete structure of the small-subunit processome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		L44 G45 L68 L69 F70 F87 H88 R103 Q146 R344 H364 R381 D383 Q385 Q387 K395 G400 R401 G403 S405 T406
Binding residue
(residue number reindexed from 1)		L26 G27 L50 L51 F52 F69 H70 R85 Q128 R326 H346 R363 D365 Q367 Q369 K377 G382 R383 G385 S387 T388
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum5wlc
PubMed28945246
UniProtQ06078|UTP21_YEAST U3 small nucleolar RNA-associated protein 21 (Gene Name=UTP21)

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