Structure of PDB 7mq8 Chain LS Binding Site BS01

Receptor Information
>7mq8 Chain LS (length=453) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVAAAEEERRLRQRNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLR
KKPVWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQ
HAMGGVPAWAEDDLLQRTGNFISTSTSLPRGILKMKNCQHANAERPTVAR
ISSVQFHPGAQIVMVAGLDNAVSLFQVDGKTNPKIQSIYLERFPIFKACF
SANGEEVLATSTHSKVLYVYDMLAGKLIPVHQVRGLKEKIVRSFEVSPDG
SFLLINGIAGYLHLLAMKTKELIGSMKINGRVAASTFSSDSKKVYASSGD
GEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYN
QDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASEKMKEAVRLVH
LPSCTVFSNFPVIKNKNISHVHTMDFSPRSGYFALGNEKGKALMYRLHHY
SDF
Ligand information
>7mq8 Chain L0 (length=242) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucgauguggugacgucgugcucucccgggccggguccgcggaccccgg
cccgaccucgcgcgggguccucugacgcggcagacagcccucgcugucgc
cgacuugcgggcggccccccuccgcggcggugggggugccgucccgccgg
cccgugcgucggcuccgggcccuugcggugcuccuggagcgcuccggguu
gcaggugcccgaggccgaugagaaaagccuucucuagcgauc
...................<<.<<....<<<<<<<<<<<<>>>>>>>.>>
>>><<<<<<<..>>>>>>>....>>>>.<<<<<......>>.>>><<<<.
>>>>...<<<<<<<<<<<<<.<<<...>>>.>>>>>.>>>>>.>>>..<<
<<<<..>>..>>>>....................................
...............<<.>>......................
Receptor-Ligand Complex Structure
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PDB7mq8 Nucleolar maturation of the human small subunit processome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		I235 N240 H316 S317 K318 H334 Q335 R337 I343 I361 A362 R384 Y427 N445 K494 K496 N512 K517 N518
Binding residue
(residue number reindexed from 1)		I132 N137 H213 S214 K215 H231 Q232 R234 I240 I258 A259 R281 Y324 N342 K391 K393 N409 K414 N415
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031965 nuclear membrane
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (Gene Name=UTP18)

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