Structure of PDB 8onz Chain LR Binding Site BS01

Receptor Information
>8onz Chain LR (length=153) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNLRTQKRLAASVLGCGEGKVWLDPNEVSEISNANSRQSIRKLVADGLII
KKPVTMHSRSRARELNLARRIGRHRGFGKRKGTADARMPQQVLWMRRQRV
LRRLLVKYRASGKIDKHLYHELYHLAKGNTFKHKRALVEHIHRAKAEKAR
ERQ
Ligand information
>8onz Chain 1 (length=270) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augaaaagcacuuugaaaagaggguuaaauagcaccuucaaugagaacuu
gaaguuccaugugaacagcgguuggacauggguugccgguuaauauuccg
gcacccggaagagcccgacacuucugucgggucaaggguugggcacguug
ggcuuugggcgcgcccugggagcagagggccucuagccgggcaaccggcc
ggcggcccucagcacccgggguagcccuuagcaggcuucggccguccggc
gugcgguuaacaaccaacuu
..........<<<<....>>>>.............<<<<<<.......>>
>>>>..<<<<<<...<<.....>>.>>>>>>...<<<<<........>>>
>>..........<<<<<<<......>>>>>>>.<<<<<<<<.<<<<<<<.
..<<..<<<<...<<<<<<<.<<.<<<<<<<.<<.<<<<<....>>>>>.
>>.>>>>>>>.>>.>>>>>>>..>>>>..>>..<<<....>>>....>>>
>>>>......>>>>>..>>>
Receptor-Ligand Complex Structure
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PDB8onz Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Resolution2.94 Å
Binding residue
(original residue number in PDB)
V2 N3 L4 R5 T6 K8 R9 L10 W23 L24 P26 R38 K43 K53 R76 R81 R88 M89 V101 R104 S112 G113 K114 H134 K135 R136 H143 K146
Binding residue
(residue number reindexed from 1)
V1 N2 L3 R4 T5 K7 R8 L9 W22 L23 P25 R37 K42 K52 R75 R80 R87 M88 V100 R103 S111 G112 K113 H133 K134 R135 H142 K145
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019887 protein kinase regulator activity
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
GO:0034198 cellular response to amino acid starvation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8onz, PDBe:8onz, PDBj:8onz
PDBsum8onz
PubMed38267453
UniProtG0S9T3

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