Structure of PDB 7mqa Chain LP Binding Site BS01

Receptor Information
>7mqa Chain LP (length=566) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAEIIQERIEDRLPELEQLERIGLFSHAEIKAIIKKASDLEYKIQRRTLF
KEDFINYVQYEINLLELIQRRRTRIGYSFKKDEIENSIVHRVQGVFQRAS
AKWKDDVQLWLSYVAFCKKWATKTRLSKVFSAMLAIHSNKPALWIMAAKW
EMEDRLSSESARQLFLRALRFHPECPKLYKEYFRMELMHAEKLRKEKEEF
SEEILKGELAWIIYKNSVSIIKGAEFHVSLLSIAQLFDFAKDLQKEIYDD
LQALHTDDPLTWDYVARRELEAKAVEVGRKEERCCAVYEEAVKTLPTEAM
WKCYITFCLERFTKLRGKRLERTMTVFRKAHELKLLSECQYKQLSVSLLC
YNFLREALEVAVAGTELFRDSGTMWQLKLQVLIESKSPDIAMLFEEAFVH
LKPQVCLPLWISWAEWSEGAKSQEDTEAVFKKALLAVIGADSVTLKNKYL
DWAYRSGGYKKARAVFKSLQESRPFSVDFFRKMIQFEKEQESCNMANIRE
YYERALREFGSADSDLWMDYMKEELNHPLGRPENCGQIYWRAMKMLQGES
AEAFVAKHAMHQTGHL
Ligand information
>7mqa Chain L2 (length=177) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauaguguguuacuaaaccacgaggaagagag
guagcguuuucuccugagcgugaagccggcuuucuggcguugcuuggcug
caacugccgucagccauugaugaucguucuucucuccguauuggggagug
agagggagagaacgcggucugaguggu
..................................<<<<<.....<<....
...<<<<<<<<<<<<....<.......<<<<....<<<<<<<<......>
>>>>.>>>...>>>>.........>..<<<<<<<<<<.....>>>>>>.>
>>>>>>>>>>>>>>>...>>..>>>>>
Receptor-Ligand Complex Structure
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PDB7mqa Nucleolar maturation of the human small subunit processome.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
M1 R47
Binding residue
(residue number reindexed from 1)
M1 R47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtQ9NYH9|UTP6_HUMAN U3 small nucleolar RNA-associated protein 6 homolog (Gene Name=UTP6)

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