Structure of PDB 7qca Chain LO0 Binding Site BS01

Receptor Information
>7qca Chain LO0 (length=198) Species: 1358809 (Spraguea lophii 42_110) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIGKRIVIDAIGHVAGKLAGHIAKELMCGIEVVIVHAENVMFTGPIKRGV
GKFNSHLNKSCSYNPLRGPFHLRSPSMHLMKVIKRKLPHRKSKGQIALKR
LQVFDGCPTEYLSVEKMVCPRDKLEYTTSPIRKSYKLGDLMIKFGWKYES
VVEKMNQNEEQFKIEETEKQKVKEQKIEELKKSNKFQQRVEEIMVQMA
Ligand information
>7qca Chain L50 (length=2499) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaccacacacaagggaucguuuggcuccugggacgaggaagggcgcagc
agagagcgauaugugugggagcagcagcaaugaccacacguccccgaaua
cagcauagugcuggaguacuccuuggaauuaagcauaugaguaaaggaag
gaaaagaaacuaacgaggauucccguaguagcggcgagugaacagggaac
aguccaacaguguaauucucaaaugagaaguugucaaaaggaagaagaug
ugaaucagaaagaaaagcugaacgauacagggugauagucccguaguguc
uucuuacauacggugaguagcugugcucgguaaugcacagugaagaggug
gcagugugcaucuaagacuaaauacaacaggagaccgauagcaaagaagu
agguugaccgaaaacagugaaauuguguguggacccgaauggaucgggcc
cgucuugaaacacggaccaaggagugcacauacacugcaaguugagcaga
ggaagucugugaggcguagugaagacggaaagcagugugagugcgacccg
auagacuugugaacuauaccuuguugcugugaaggcuggcgaaagccagc
uggaggcggcaagccguauugaucugcaaaucauuggcguaagcagggua
uaggggcgaaagaccaaucgaacagucuaguugcugguucccuccgaaau
gucuaucaggacagcgcgcacgcagagagaagcaagguagagcaugggcc
gguauccuuaaggagacggacgaacugcgaaugugcuuuucuucuaugca
agcguagugggcgaguucugguaagcaggacuggcgaagaggaaugaacc
uggcacugugcuaaggaacccaaugucuggacagagaccgaaagagguag
gugaauaaaauucaucugcucugaaaauugauggcgcuuaccagacaucc
gaugcacaguuagcagguaggagggcgugugucuacuggcgaagguaccg
agugaucggugguggagguagaugcagagcagaucuuggugguaguagcg
auaauuugucuucagcggcaaagacugaggaggagaaggguuucuucuca
uaagaagagugagccgggucuaagcgaguguguagaagcaugagcgaagg
agaaacagguugauauuccugugccugugcugucguacggcaacguguau
uagcuugucgacacgaacaucuagacaaagcagaaacaccuuuucuguuc
aaggggaaaaagaccacugagacggaucaucuggcgacgugguuuuauau
cugugaccaggccugagccugguuuguugaggauggucguccaugaaaag
acaacuauauggcagcacaguccguaccaaccguaucaggacuccaaggu
gaagagccucuaguggauguuuuacacauguaagggaauucggcaaaaug
gaugcguaacuucgggagaaguauugguucaauugugaacucauugugac
aaggggaaucugacuguuuaguaaaaacauagcuucaugaagagagauga
agugaguucugcccggugcucggucgugacacggaggaaaugccagaaag
cacggguuaacggcgggaguaacuaugacucucuuaagguagccaaacgc
cucgucauuuaaauggugacgcgcaugaauggaaugacgagauucccacu
gucccuacauguagacuagcgaacccauuuccaggggaacgggccuggac
ggccagcggggaaagaagacccuguugagcuugacucuaguguggccaag
uugugacgauugaggcgagcgccaugaucaucacgacacacuuguuuaag
gacaaaggccagauggggaguuuggcuggggcgguacgaccacagaauca
gaacguggucgaccgaagguacucacagcgagacgagaacacucguguag
agcauaaggacuaaagagugccugagugugagcacuacugcuugcaugag
gggaaacccgggccuagcgauccuacgcauacgagacacuuguggcgugg
gugucagaaaaguuaccacagggauaacuggcuuguggccgccgagcgua
gaaagcgacgcggcuuuuugauucuucgaugucggcucuuccuagcaugg
ccaugcagccguggcgaaguguuggauuguucacccacuaacagggaacg
ugagcuggguuuagaccgucgugagacagguuaguuuuauccuacugucc
aaacaguugaagggaguguggauuaguacgaaaggaaacccacacgugac
cucuggugcagcgggugugcggaagugcaacugccaugcuacgucuccuc
aagcauagcuggaagccucuaagcuagaaaugaguccugacucuggaaga
cggccgggaagacgacccguaguuaacagcgguguuguacgauaugagcu
uucuauuguaguagcgaguauuugagacacugguuguuaccaccgucgu
....<<<<<<<<<......((..((<<<<<<...<......<<<<<<.((
.....>>>....<<<<<<..<..))..>.....>>>>>>...>>>.....
<<<<<...>>>>>>....<<<<<<.....<......>......>>>>>.>
.........<<....>>..<<<<<......<<.....>>.....>>>>>.
.<<<...........<<<<<<..>>>>>>............<<<<<<<<<
<...<<<<.........>>>>((......<<<.....))>>>...>>>>>
>>>>>..............<<<<<<<........>>>>>>>....<<<<<
..<<<<<.>>>>>..>>>.........>>>>>>.))..............
.<<....>>....)).......>>>>>>>>>..<<<<<.....>>>>>.<
<<<........>>>><<<<<<....<<<<.<<<<<<<<..<<<..<<<<<
.....>>>>>..>>>...<<....>>.....>>>>>>>>.>>>>..<<.<
..<<<<<.<<.....<<<<<<<<<<<<<<....<<<<<<<....>>>>>>
>.....>>>>>.<<<..<<.<<........>>>>.>>>....>>>>>>>>
>...<<.......>>......>>>>>>...>..>.>>..<<<<<<....<
<<<<....>>>>><<<<<<..<<<<<.<<<<<<<.....<<<......<<
<...<<<<..>>>>..>>>.....>>.>.....>>>>>..>>>>>..>>.
.>>>>.>>..<<.<<<<<<<.....>>>>>>>.>>....<<<......>>
>...<<<<<<<...<<<.((...<<<<<<<.....<......<<.<<<<<
<<<<<<...>>>>>>>>>>>>>..........))..>...>>>>>>>>>>
...>>>>>>>.........>>>>>><.<<<<<<<<<<......<.<<<<<
<....>>>>>>.>...>>>>>>>>>>..>.....>>>>>><<.....<<.
....<<<<<<......>>>>>>.<<<.....<<<<..<<...<<<<<<..
..>>>>>>....((<<<<<<...<<..<<<<......>>>>..>>....>
>...<<<<<........>>>>>))<<<<<<<<<<..<<<....>>>....
<<<.<<<<<...<<<<.<<<<..<<<<<<<<<<<<...[[..>>>>>><<
..<<<..<.<<<<<<<<.....<<<<...>>>>.....>>>>>>>>.>.>
>>..>><<<<<<....>>>>>>>>>>>>...>>>>.>>>>.........>
>>>>>>>...>>>>>>>>>>>>>>..>>..<<......>>.>>>>.<<<<
.....>>>>..>>>....<<.....<<<<<<<.<<.........<.....
<<<<<.....<..>......>>>>><<<<<<....>>>>>>.........
...<<<<<<<<<..<<<.........>>>..<<<<<<<........>>>>
>>>..<<<..<<<..<<<<<<<.<.<<.....<<........>>.....>
>>>>>>>..>>>>><<<<<<.......>>>>>>........<........
...<<<<<<.....>>>>>>.....>.....>>.>..>>.>>>>>>>..>
..>>.>>>>>>>..>>..>>....>>....<<<<<........>>>>>..
[[.<<<..<<<.[[......<<<<.[[<<<<..<<<<<.<<.<<<<<..<
<<<<<<.<<<<..<<<<..>>>>..>>>>.>>>>>>>...<<<....>>>
......>>>>>.>>..>>>>>...<.<.....>.>..<<<<<<.......
....>>>>>>..<<...<<<<<<<...<<<<<.........>>>>>....
<<..[.(((.>>...>>>>>>>...<<<<<<<<......>>>>>>>>..<
<<....>>>.>>)))]......<<<<<<.<<<...>>>>>.>>>>>>>>>
..........>>>>..]]>>>>.......<<.<.<.<<<<<<...<<...
....>>...>>>>>>...>>..>>.......<<<<<.<<<<<<..<<<.<
<<<<......>>>>>...>>>.<<<.........>>>.....>>>>>..>
...>>>.>>....<<<<<<<....>>>.>>>>....]]..>>>.>>>.]]
...<<<....<<<<.<<<<<<..................>>>>>><.<<<
...<<<<...<<<<.<<<<.]]...>>>>.>>>>...>>>>.>>>.><<<
<....<<<<<...........>>>>>....>>>>>>>>....>>>...<<
<<<.<<<<.......>>>>....<<<<<<<<<<<<<....<<<<<..<<<
..<<<...>>>.>>>..>>>>>...>>>>>>.>>>>>>>...>>>>>..
Receptor-Ligand Complex Structure
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PDB7qca Spraguea lophii ribosome
Resolution2.79 Å
Binding residue
(original residue number in PDB)		G16 K17 K24 T43 K47 R48 G51 S55 K59 S60 C61 Y63 N64 R67 P69 F70 H71 L72 R73 V82 R85 K86 H89 R90 K91 S92 K93 I96 T127 S129 R132 K133 K143 F144 K147 Y148
Binding residue
(residue number reindexed from 1)		G16 K17 K24 T43 K47 R48 G51 S55 K59 S60 C61 Y63 N64 R67 P69 F70 H71 L72 R73 V82 R85 K86 H89 R90 K91 S92 K93 I96 T127 S129 R132 K133 K143 F144 K147 Y148
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qca, PDBe:7qca, PDBj:7qca
PDBsum7qca
PubMed
UniProtS7XUD8

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