Structure of PDB 8br8 Chain LO Binding Site BS01

Receptor Information
>8br8 Chain LO (length=203) Species: 184922 (Giardia lamblia ATCC 50803) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAYKYVQELWRKKQSEALHYLFRLRTWEYRQLNAIKRCSHPTRPEKARRL
GYKAKRGYVVYRVRVRRGGRKRQCVHGISYGKPRNIGIVGLKPSRSLRAL
AEQKVGRRLPSLRVLNSYWVAQDGSYKWYEVILIDPFHPWIRNDPKINWI
CNPVMKRRECRGLTSAGRKARGLHNKGIGAMKLRPSKRAAWKRNHTRSLR
RYR
Ligand information
>8br8 Chain LD (length=142) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcacgccccgccggcggaugccucggcccgggcggcgacgaagagcgcgg
cggagcgcgagacgcggugcggacccgcccgccccgagaagcaccgaucc
ucgaacgcagcgcgccccggcgccgccgccucggcgccugcc
..........................................<<<<<<<(
(....>>>>.....<<<<<<...<..))..>.........>>>>>>...>
>>....<<...>><<<..>>>.....................
Receptor-Ligand Complex Structure
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PDB8br8 Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		R38 R57 V60 Y62 R109 L113 D136 H139
Binding residue
(residue number reindexed from 1)		R37 R56 V59 Y61 R108 L112 D135 H138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8br8, PDBe:8br8, PDBj:8br8
PDBsum8br8
PubMed36912103
UniProtA8B8Z6

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