Structure of PDB 7mq9 Chain LO Binding Site BS01

Receptor Information
>7mq9 Chain LO (length=848) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFAYRFSNLLGTVYRRGNLNFTCDGNSVISPVGNRVTVFDLKNNKSDTLP
LATRYNVKCVGLSPDGRLAIIVDEGGDALLVSLVCRSVLHHFHFKGSVHS
VSFSPDGRKFVVTKGNIAQMYHAPGKKREFNAFVLDKTYFGPYDETTCID
WTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFESNSL
DLYSLSQDGVLCMWQCDTPPEGLRLKPPAGWKADLLQRKVKYSRLAKYFF
NKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQS
IASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS
PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT
SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFE
IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFD
SWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIE
GRHDLKTGRKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIY
HVREQILMKRFEISCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGQEDGV
AIPLPGVRKGDMSSRHFKPEIRVTSLRFSPTGRCWAATTTEGLLIYSLDT
RVLFDPFELDTSVTPGRVREALRQQDFTRAILMALRLNESKLVQEALEAV
PRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLLMLHGQ
KLKSRAGTLLPVIQFLQKSIQRHLDDLSKLCSWNHYNMQYALAVSKQR
Ligand information
>7mq9 Chain L0 (length=242) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucgauguggugacgucgugcucucccgggccggguccgcggaccccgg
cccgaccucgcgcgggguccucugacgcggcagacagcccucgcugucgc
cgacuugcgggcggccccccuccgcggcggugggggugccgucccgccgg
cccgugcgucggcuccgggcccuugcggugcuccuggagcgcuccggguu
gcaggugcccgaggccgaugagaaaagccuucucuagcgauc
...................<<.<<....<<<<<<<<<<<<>>>>>>>.>>
>>><<<<<<<..>>>>>>>....>>>>.<<<<<......>>.>>><<<<.
>>>>...<<<<<<<<<<<<<.<<<...>>>.>>>>>.>>>>>.>>>..<<
<<<<..>>..>>>>....................................
...............<<.>>......................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7mq9 Nucleolar maturation of the human small subunit processome.
Resolution3.87 Å
Binding residue
(original residue number in PDB)		Y56 G76 I118 T139 F141 R175 I180 Y181 Y182 K188 D209 K227 K271 F281 E285 G286 D287 F288 R661 D673
Binding residue
(residue number reindexed from 1)		Y55 G75 I117 T138 F140 R174 I179 Y180 Y181 K187 D208 K226 K239 F249 E253 G254 D255 F256 R629 D641
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031981 nuclear lumen
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mq9, PDBe:7mq9, PDBj:7mq9
PDBsum7mq9
PubMed34516797
UniProtQ15269|PWP2_HUMAN Periodic tryptophan protein 2 homolog (Gene Name=PWP2)

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