Structure of PDB 4v3p Chain LM Binding Site BS01

Receptor Information
>4v3p Chain LM (length=140) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSKRGRGGSAGNKFRMSLGLPVAATVNCADNTGAKNLYIISVKGIKGRLN
RLPSACVGDMVMATVKKGKPDLRKKVMPAVIVRQRKPWRRKDGVFMYFED
NAGVIVNPKGEMKGSAITGPIGKECADLWPRIASAANAIV
Ligand information
>4v3p Chain L1 (length=3352) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgcgaccccaggucaggcgggacuaccgcugaguuuaagcauauaaaua
agcggaggagaagaaacuuacaaggauuccccuaguaacggcgagcgaac
cgggagcagcccaagaaucgggcggcugugccguccgaauuguagucugg
agaggcguccucagcgacggaccgggcccaaguccccuggaaaggggcgc
cugggagggugagagccccguccggcccggacccugucgccccacgaggc
gccgucaacgagucggguuguuugggaaugcagcccaaaucgggcgguag
acuccguccaaggcuaaauacaggcgagagaccgauagcgaacaaguacc
gcgagggaaagaugaaaaggacuuugaaaagagagucaaagagugcuuga
aauugccgggagggaagcggaugggggccggcgaugcgccccggccguau
gcggaacggcucuugcugguccgccgcucggcucggggcguggacuguug
ucggccgcgccggcggccaaagcccgggggcuccgcgcccccggcagccg
ucgucggcacggccgguacccgcgcgccgaaaggcgugccccucggggca
cugcgcugcaacgcccugcgggcuccccauccgacccgucuugaaacacg
gaccaaggagucugacaugcgugcgagucgacggguucugaaaccuggga
ugcgcaaggaagcugacgagcgggaggcccucacgggccgcaccgcuggc
cgacccugaucuucugugaaggguucgaguuggagcacgccugucgggac
ccgaaagauggugaacuaugccugagcggggcgaagccagaggaaacucu
gguggaggcucgaagcgauacugacgugcaaaucguucgucugacuuggg
uauaggggcgaaagacuaaucgaaccaucuaguagcugguucccuccgaa
guuucccucaggauagcuggagcccauuacgaguucuaucagguaaagcc
aaugauuagaggcauuggggacgcaacguccucgaccuauucucaaacuu
uaaauagguaggauggcgcggcugcuucggugagccgugccauggaaucg
ggugcuccaagugggccauuuuugguaagcagaacuggcgaugcgggaug
aaccggaagccggguuacggugcccaacugcgcgcuaaccuagaacccac
aaaggguguuggucgauuaagacagcaggacgguggucauggaagucgaa
auccgcuaaggaguguguaacaacucaccugccgaaucaacuagccccga
aaauggauggcgcugaagcgcgcgacccacacccggccaucugggcgagu
gccaugccccgaugaguaggagggcgcggcggccaugcaaaacccgggcg
cgagcccgggcggagcggccgucggugcagaucuuggugguaguagcaaa
uauucaaaugagaacuuugaaggccgaagaggagaaagguuccaugugaa
cggcacuugcacauggguaagccgauccuaagggaagggguaaccccggc
agauagcgcgaucacgcgcauccccgaaagggaaucggguuaagauuccc
gagccggguguggcgguugacggcgacguuaggaaguccggagacgccgg
cgggggccucgggaagaguuaucuuuucugcuuaacggccugccaacccu
ggaaacgguucagccggagguagguccaguggccggaagagcacacgucg
cgcgguguccggugcgcccccggcggcccaugaaaauccggaggaccgag
uaccgucacgcccggucguacucauaaccgcaucaggucuccaaggugaa
cagccucuggccaauggaacaauguaggcaagggaagucggcaaaacgga
uccguaacuucgggaaaaggauuggcucugaggacugggcucgggggucc
cggccccgaacccgucggcugucggcggauugcucgagcugcucacgcgg
cgagagcgggucgccgcgugccggccgggggacggaccgggaaucgcccc
uucgggggcuuuccccgagcaugaaacagucgacucagaacugguacgga
caaggggaauccgacuguuuaauuaaaacaaagcauugcgaugguccucg
cggaugcugacgcaaugugauuucugcccagugcucugaaugucaaagug
aagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacucucu
uaagguagccaaaugccucgucaucuaauuagugacgcgcaugaaugaau
uaacgagauucccacugucccugucuacuauccagcgaaaccacagccaa
gggaacgggcuuggcggaaucagcggggaaagaagacccuguugagcuug
acucuaguccgacuuugugaaaugacuugagagguguaggauaaguggga
gcccucacgggcgcaagugaaauaccacuacuuuuaacguuauuuuacuu
auuccgugggucggaagcggggcaugccccaaggcccggucuuaccgggc
cgauccgggcggaagacauugucagguggggaguuuggcuggggcggcca
aucuguuaaaagauaacgcagguguccuaagaugagcucaacgagaacag
aaaucucguguggaacaaaaggguaaaagcucguuugauucugauuucca
guacgaauacgaaccgugaaagcguggccuaucgauccuuuagacuucgg
aguuugaagcuagaggugucagaaaaguuaccacagggauuacuggcuug
uggcagccaagcguucauagcgacguugcuuuuugauccuucgaugucgg
cucuuccuaucauugcgaagcagaauucaccaaguguuggauuguucacc
caccaauagggaacgugagcuggguuuagaccgucgugagacagguuagu
uuuacccuacugaugacagugucgcgauaguaauucaaccuaguacgaga
ggaaccguugauucacacaauuggucaucgcgcugguugaaaagccagug
gcgcgaagcuaccgugugccggauuaugacugaacgccucuaagucagaa
uccaagcuagcaugcgacgccugcgcccgccgcccgccccgacccacguu
aggggcgcuugcgcccccaagggcccgugccauuggcuaagccgguccgg
ccgaagugccgcggucggccgccucgaagcucccuucccaacgggcggug
ggcuaauccuuugcagacgacuuaaauacgcgacggggauuguaaguggc
agaguggccuugcugccacgauccacugagaucccgcgucgcacggauuc
gu
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...>>>>>>..>..<<<<.<<<<<.....>>>>>.>>>>....<<<....
..>>>...<<<<<<<...<<<(((.....<<<<<<...............
...<<<.<<<<<<.<<<.......<<<<<.<<....<<.........>>.
...>>.........<<......>>...>>>>>...>>>.>>>>>>>>>..
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....>>>>>.>>>>....>>>>>>..<<<<<<<<........<<<<<<<.
...>>>>>>>......>>>>>>>>........>>>>>><<.....<<...
..<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...
<<.....>>.>>>>>>....((<<<<<<...<<<...<<<....>>>...
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<<<.<<..<<<...<<<<.......>>>>..<.....<..........<<
.....<<<<...>>>>......>>.........>......>.<<.<<...
..>>>>...>>>.....>>>>>.>>>>.........>>>>>>...>....
.>>>.>>>>>>>>>.>>>..>>.....<<......>>>>>>>..<<<...
..>>>...>>>>..<<<<.....<<<<<<<.<<...............<<
<<<.....<..>......>>>>><<.<<<<<<<<<<<.<<<<<<<<<<<<
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....>>>>>..>>>>>>>>>......>>>>>..>>>>>>.>>........
....<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<...
.>>>.......>>>>>>>...<<<.<<<..<<<<<<....<<<.....<<
<<....>>>>.....>>>.>>>>..>>>>><<<<<<.......>>>>>>.
.......<...........<<<<<.......>>>>>.....>....>>>.
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<........>>>>>....<<<<<..<<<.<<......<<<<.<<<<<<..
<<<<<.<<<.<<<...<<<<<<<<<.<<<<<<<...........<<<<..
<<<......>>>............>>>>..>>>>>>>..>>>>>>>>>..
.<<<<<....<<<<<...<<<<....>>>>..<<<<<<<<...>>>>>>>
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...>>>>>>.....<<...(((>>....>>>>>>>...<<<..<<<<...
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..]].>>>>>>>>>>..........>>>>..>>>>>>.......<<.<..
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......>>>>>.><<<<<....<<<...<<<<<<<<<......>>>>...
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..
Receptor-Ligand Complex Structure
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PDB4v3p The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes.
Resolution34.0 Å
Binding residue
(original residue number in PDB)
M1 S2 K3 G8 S9 G11 R15 S17 L18 G19 P21 A24 T25 I40 S41 V42 K43 G44 I45 K46 G47 R48 L49 N50 R51 L52 P53 M62 T64 K66 K74 R85 K86 R89 F95 N101
Binding residue
(residue number reindexed from 1)
M1 S2 K3 G8 S9 G11 R15 S17 L18 G19 P21 A24 T25 I40 S41 V42 K43 G44 I45 K46 G47 R48 L49 N50 R51 L52 P53 M62 T64 K66 K74 R85 K86 R89 F95 N101
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v3p, PDBe:4v3p, PDBj:4v3p
PDBsum4v3p
PubMed25376914
UniProtQ5I7K4

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