Structure of PDB 5wlc Chain LL Binding Site BS01

Receptor Information
>5wlc Chain LL (length=475) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPVLQSAYDPSGQYLCYVTVALDKQRVGVQPTQRWNENFLYLEDSKLKVT
CLKWVNDTVAIILGMNNGEIWLYSVLANEVTYKFTTGNSYEIKDIDLMGN
QLWCIDSSDAFYQFDLLQFKLLQHFRINNCVQLNKLTIVPAGDSVAQLLV
ASHSISLIDIEEKKVVMTFPGHVSPVSTLQVITNEFFISGAEGDRFLNVY
DIHSGMTKCVLVAESDIKELSHSGQADSIAVTTEDGSLEIFVDPLVSGNK
SKKSSKKIQIVSKDGRKVPIYNAFINKDLLNVSWLQNATMPYFKNLQWRE
IPNEYTVEISLNWNNKNKSADRDLHGKDLASATNYVEGNARVTSGDNFKH
VTGTVTVILSQALQSNDHSLLETVLNNRDERVIRDTIFRLKPALAVILLE
RLAERIARQTHRQGPLNVWVKWCLIIHGGYLVSIPNLMSTLSSLHSTLKR
RSDLLPRLLALDARLDCTINKFKTL
Ligand information
>5wlc Chain L0 (length=488) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagacaagugcuugucguucguuaauggccucgucaaacgguggagaga
gucgcuaggugaucgucagaucugccuagucucuauacagcguguuuaau
ugacauggguugaugcguauugagagauacaauuugggaagaaauuccca
gaguguguuucuuuugcguuuaaccugaacagucucaucgugggcaucuu
gcgauuccauuggugagcagcgaaggauuugguggauuacuagcuaauag
caaucuauuucaaagaauucaaacuugggggaaugccuuguugaauauuc
uucaaguguaaccuccucucaaaucagcgauaucaaacguaccccgugaa
acaccgggguaucuguuugguggaaccugauuagaggaaacucaaagagu
gcuaugguauggugacggagugcgcuggucaagaguguaaaagcuuuuug
aacagagagcauuuccggcagcagagauuucagcuguu
<<<<<<<<<..>>>>>>.>>>............<<<<<<<<.<<...<<<
<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>...>>.>>>......>
>>>>..<<<<<<..<<<<<..<<<<<<<<<<.<<<<<<<<....>>>>>>
>>.>>>>>>>>>>.>>>>>.>>>>>>.......<<<<<<<<<<<......
.....>>>>>.>>>>>>.........................<<<...>>
>.........................<<<<<..<<<<<<<..<<<..>>>
..>>>>.>>.>>>>>>.....<<<<<<...<<<<<<<<<<<<<<<<....
....>>>>>>>.>.>>>>>>>>....>>>>>>..................
...............<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>
>.>>>...>>>>.>>>><<<<<.<<<..>>>.>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wlc The complete structure of the small-subunit processome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
H346 G359 N360 R362 E454 R460 R490 Q491 H493 R494
Binding residue
(residue number reindexed from 1)
H325 G338 N339 R341 E372 R378 R408 Q409 H411 R412
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0033553 rDNA heterochromatin
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum5wlc
PubMed28945246
UniProtQ04177|UTP5_YEAST U3 small nucleolar RNA-associated protein 5 (Gene Name=UTP5)

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