Structure of PDB 8pv5 Chain LK Binding Site BS01

Receptor Information
>8pv5 Chain LK (length=158) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEIKIIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATADWKGLR
VTVRLTIQNRQAQVSVVPTASALIIRALKEPPRDRKKEKNIKHNKSVSLD
EIIEIARTMRFKSFSKDLKGGVKEILGTAFSVGCQVDGKSPKAISDAIEA
GEIDIPDE
Ligand information
>8pv5 Chain C1 (length=3060) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacuau
gcuuggauagggugaagccagaggaaacucugguggaggcucgcagcggu
ucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacuaa
ucgaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcag
ugucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaa
gaagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacua
gugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgc
gggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguua
guacaucuugacagcaggacgguggccauggaagucggaauccgcuaagg
acuguguaacaacucaccugccgaauguacuagcccugaaaauggauggc
gcucaagcgucccacccauaccccgcccucaggguagaaacgaugcccug
aggaguaggcggccguggaggucagugacgaagccuagggcgugagcccg
ggucgaacggccucuagugcagaucuuggugguaguagcaaauacuucaa
ugagaacuugaaggaccgaaguggggaaagguuccaugugaacagcgguu
ggacauggguuagucgauccuaagccauagggaaguuccguuucaaaggg
gcacucgugccccguguggcgaaagggaagccgguuaauauuccggcacc
uggauguggguuuugcgcggcaacgcaacugaacgcggagacgacggcgg
gggccccgggcagaguucucuuuucuucuuaacggucuaucacccuggaa
acaguuugucuggagauaggguuuaauggccggaagagcccgacacuucu
gucggguccggugcgcucucgacgucccuugaaaauccgcgggagggaau
aauucucacgccaggucguacucauaaccgcagcagguccccaaggugaa
cagccucugguugauagaacaauguagauaagggaagucggcaaaauaga
uccguaacuucgggaaaaggauuggcucuaaggguugguaacaaccaacu
uagaacugguacggacagggggaaucugacugucuaauuaaaacauagca
uugcgauggccagaaagugguguugacgcaaugugauuucugcccagugc
ucugaaugucaaagugaagaaauucaaccaagcgcggguaaacggcggga
guaacuaugacucucuguagccaaauggauuaacgagauucccacugucc
cuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaau
cagcggggaaagaagacccuguugagcuugacucuaguuugacauuguga
aaagauuuuuuuacuuauucaaugaagcggggcuggacuugcguccaacu
ucuggaguuaagguccuucgcgggccgacccggguugaagacauugucag
guggggaguuuggcuggggcggcacaucugugcagguguccuaagggggg
cucauggagaacagaaaucuccaguagaacaaaaggguaaaaguccccuu
gauuuugauuuucagugugaauacaaaccaugaaaguguggccuaucgau
ccuuuagucccucgaaauuugaggcuagaggugccagaaaaguuaccaca
gggauggcuuguggcggccaagcguucauagcgacgucgcuuugauccuu
cgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguugga
uuguucacccacuaauagggaacgugagcuggguuuagaccgucgugaga
cagguuaguuuuacccuacugaugaacucgucgcaaugguaauucagcuu
aguacgagaggaaccgcugauucagauaauugguuuuugcgguuguccga
ccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccuc
uaagucagaauccaugccagaacgcgacgauacuacccgcacguuguaga
cguauaagaauaggcuccggccucguauccuagcaggcgauuccuccgcc
ggccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgc
gggaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaag
caguagaguagccuuguuguuacgaucugcugaggguaagcccuccuucg
ccuagauuuc
........................<<<<<<.....<......>......>
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....<<<.....))>>>.>..>>..>>.>>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<..(((((
(>>>>>..>>>....>.............................<<...
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..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<...<<....>>..
.>>>>.>>.>>....>>>>.>>>>>>>>>.<<.<...<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.
<<.<<........>>>>>>>>....>>>>>>>>>...<<.......>>..
....>>>>>>......>.>>...<<<<<......<<<....>>>..<<<<
<<<<<.....<<.<<<<<<<.....<<<........>>.>.....>>>>>
...<<<<.<<<<.<......>>>>>.>>>>.....>>>>...>>>>>>>.
>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<
<<<<<...<<<(((.....<<<<<<.....<<..........<<<.<<<<
<<<<<<.......<<<<<.<<<...<<.........>>...>>>......
...<<......>>...>>>>>...>>>>>>>>>>>>>..........)))
.>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>
>>>....>>>>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>........>>>>>><<.....<<.....<<<<<<
.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.....>
>.>>>>>>....((<<<<<<...<<<...<<<....>>>........<<<
<<<....>>>>>>....>>>....>>...<<<<<........>>>>>))<
<<<.<<<<.<<<....<<<....>>>...<.((<<<<<<...<<<<.<<<
<<<<.<<<<<.<<<<...[[..>>>>.><...<<<<<....<<<<<<...
.<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<......
>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>...>.....
>>>...>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<...
..>>>>..>>>>..<<<<.....<<<<<<<.<<.........<.....<<
<<<....<....>.....>>>>><<.<<<<<<<<<<<....>>>>>..>>
>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<....<<<<.....>>>>......>>>>>>>.........<<.<<<<
<<....<<<.....<<<<....>>>>.....>>>.>>>>..>>>>.<<<<
<<.......>>>>>>......<<..>>......>>.>>>>>>>..>..>>
.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<
<<<..<<<........<<<<<.<<<<<<..<<<<<.<<<<<<<<..<<<<
<<<<..>>>>>>>>...<<<<<.....<<<<..<<<<<....>>>>>...
.......))..<<<<<.....>>>>>..>>>>..>>>>>.....>>>>>>
>>..>>>>>.......<<<<<<.<<<<<<....>>>>>>>>...<<<<<<
<...<<<<<<.......>>>>>>.....<<......>>....>>>>>>>.
...<<<<.<.<<<.....>>>.>>>>><<<<....>>>.>>>>>.<<...
<<<<<<<..<<<<.))))))>>>>>>>>>>>.....>>..>>>>..>>>>
>>>.........<<<<<<...<<.......>>...>>>>>>.........
......<<<<...<<<<..<.<<<<<<<......>>>>>>>...>.<<<.
........>>>.....>>>>.......>>>>......<<<<<<<....>>
>.>>>>........>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<..
...............>>>>>.><<<<<...<<<<....<<<<<<<<<<]]
..>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.........
..>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<...
...<<.......<<<....>>>....>>........<<<<.....<<<.<
<<<<.......>>>>>.>>>....>>>>..............>>>>>.>>
>>>...<<<<<<<.............>>....<<<<<<<<<.<<<....<
<<<....<<<<<......>>>>>...>>>>...>>>....>>>>..>>>>
>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv5 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		R16 T76 S78 R92 K96 N97 H100 F121 S122 K123 K130 E131 G134 T135 S138 K149
Binding residue
(residue number reindexed from 1)		R9 T69 S71 R85 K89 N90 H93 F114 S115 K116 K123 E124 G127 T128 S131 K142
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8pv5, PDBe:8pv5, PDBj:8pv5
PDBsum8pv5
PubMed37921038
UniProtG0SGH8

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