Structure of PDB 8bsj Chain LK Binding Site BS01

Receptor Information
>8bsj Chain LK (length=197) Species: 5741 (Giardia intestinalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRRPARCYRYQKNKPYPKSRFCRGVPDPKIRYFDLGNRRAKVNDFPYCFH
LLSGEKEQVSSEALEACRIACNKYIAKKAGKDSFHLRIRVHPFHVIRINK
MLTGMRGAWGKPQGTVARVSIGQPLLSVRCRASAKDYVKDALRRAKFKIP
GRQAIVESRNWGFTEFTKEEYEDLRERGELQYDGNNAHRISRKGPLN
Ligand information
>8bsj Chain LE (length=116) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucggccauccuacggcggaaacuccuuaacucguuccgaauuaggaag
agaagcgccgucaggccccgccaguacugcgaucggagacgucgugggaa
cacggggugccgaacu
<<<<<<<....<<<<<<<<.....<<<<<...............>>>..>
>....>>>>>>.>><<<<<<......<<<<<<.<<....>>>>>>>>...
..>>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8bsj Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Resolution6.49 Å
Binding residue
(original residue number in PDB)		Y11 E56 K57 R202 K203 G204 L206
Binding residue
(residue number reindexed from 1)		Y10 E55 K56 R192 K193 G194 L196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8bsj, PDBe:8bsj, PDBj:8bsj
PDBsum8bsj
PubMed36912103
UniProtA8BM86

[Back to BioLiP]