Structure of PDB 8pv5 Chain LJ Binding Site BS01

Receptor Information
>8pv5 Chain LJ (length=169) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KAQNPMRELRIQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYT
VRQFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELRRRNFSETGNFG
FGISEHIDLGIKYDPSIGIYGMDFYCCMTRPGERVAKRRRCKSRIGASHR
ITREETIRWFKQRFDGIVR
Ligand information
>8pv5 Chain C1 (length=3060) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacuau
gcuuggauagggugaagccagaggaaacucugguggaggcucgcagcggu
ucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacuaa
ucgaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcag
ugucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaa
gaagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacua
gugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgc
gggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguua
guacaucuugacagcaggacgguggccauggaagucggaauccgcuaagg
acuguguaacaacucaccugccgaauguacuagcccugaaaauggauggc
gcucaagcgucccacccauaccccgcccucaggguagaaacgaugcccug
aggaguaggcggccguggaggucagugacgaagccuagggcgugagcccg
ggucgaacggccucuagugcagaucuuggugguaguagcaaauacuucaa
ugagaacuugaaggaccgaaguggggaaagguuccaugugaacagcgguu
ggacauggguuagucgauccuaagccauagggaaguuccguuucaaaggg
gcacucgugccccguguggcgaaagggaagccgguuaauauuccggcacc
uggauguggguuuugcgcggcaacgcaacugaacgcggagacgacggcgg
gggccccgggcagaguucucuuuucuucuuaacggucuaucacccuggaa
acaguuugucuggagauaggguuuaauggccggaagagcccgacacuucu
gucggguccggugcgcucucgacgucccuugaaaauccgcgggagggaau
aauucucacgccaggucguacucauaaccgcagcagguccccaaggugaa
cagccucugguugauagaacaauguagauaagggaagucggcaaaauaga
uccguaacuucgggaaaaggauuggcucuaaggguugguaacaaccaacu
uagaacugguacggacagggggaaucugacugucuaauuaaaacauagca
uugcgauggccagaaagugguguugacgcaaugugauuucugcccagugc
ucugaaugucaaagugaagaaauucaaccaagcgcggguaaacggcggga
guaacuaugacucucuguagccaaauggauuaacgagauucccacugucc
cuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaau
cagcggggaaagaagacccuguugagcuugacucuaguuugacauuguga
aaagauuuuuuuacuuauucaaugaagcggggcuggacuugcguccaacu
ucuggaguuaagguccuucgcgggccgacccggguugaagacauugucag
guggggaguuuggcuggggcggcacaucugugcagguguccuaagggggg
cucauggagaacagaaaucuccaguagaacaaaaggguaaaaguccccuu
gauuuugauuuucagugugaauacaaaccaugaaaguguggccuaucgau
ccuuuagucccucgaaauuugaggcuagaggugccagaaaaguuaccaca
gggauggcuuguggcggccaagcguucauagcgacgucgcuuugauccuu
cgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguugga
uuguucacccacuaauagggaacgugagcuggguuuagaccgucgugaga
cagguuaguuuuacccuacugaugaacucgucgcaaugguaauucagcuu
aguacgagaggaaccgcugauucagauaauugguuuuugcgguuguccga
ccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccuc
uaagucagaauccaugccagaacgcgacgauacuacccgcacguuguaga
cguauaagaauaggcuccggccucguauccuagcaggcgauuccuccgcc
ggccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgc
gggaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaag
caguagaguagccuuguuguuacgaucugcugaggguaagcccuccuucg
ccuagauuuc
........................<<<<<<.....<......>......>
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>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<<...<<<<......>>>>.((..
....<<<.....))>>>.>..>>..>>.>>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<..(((((
(>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<...<<....>>..
.>>>>.>>.>>....>>>>.>>>>>>>>>.<<.<...<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.
<<.<<........>>>>>>>>....>>>>>>>>>...<<.......>>..
....>>>>>>......>.>>...<<<<<......<<<....>>>..<<<<
<<<<<.....<<.<<<<<<<.....<<<........>>.>.....>>>>>
...<<<<.<<<<.<......>>>>>.>>>>.....>>>>...>>>>>>>.
>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<
<<<<<...<<<(((.....<<<<<<.....<<..........<<<.<<<<
<<<<<<.......<<<<<.<<<...<<.........>>...>>>......
...<<......>>...>>>>>...>>>>>>>>>>>>>..........)))
.>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>
>>>....>>>>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>........>>>>>><<.....<<.....<<<<<<
.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.....>
>.>>>>>>....((<<<<<<...<<<...<<<....>>>........<<<
<<<....>>>>>>....>>>....>>...<<<<<........>>>>>))<
<<<.<<<<.<<<....<<<....>>>...<.((<<<<<<...<<<<.<<<
<<<<.<<<<<.<<<<...[[..>>>>.><...<<<<<....<<<<<<...
.<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<......
>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>...>.....
>>>...>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<...
..>>>>..>>>>..<<<<.....<<<<<<<.<<.........<.....<<
<<<....<....>.....>>>>><<.<<<<<<<<<<<....>>>>>..>>
>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<....<<<<.....>>>>......>>>>>>>.........<<.<<<<
<<....<<<.....<<<<....>>>>.....>>>.>>>>..>>>>.<<<<
<<.......>>>>>>......<<..>>......>>.>>>>>>>..>..>>
.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<
<<<..<<<........<<<<<.<<<<<<..<<<<<.<<<<<<<<..<<<<
<<<<..>>>>>>>>...<<<<<.....<<<<..<<<<<....>>>>>...
.......))..<<<<<.....>>>>>..>>>>..>>>>>.....>>>>>>
>>..>>>>>.......<<<<<<.<<<<<<....>>>>>>>>...<<<<<<
<...<<<<<<.......>>>>>>.....<<......>>....>>>>>>>.
...<<<<.<.<<<.....>>>.>>>>><<<<....>>>.>>>>>.<<...
<<<<<<<..<<<<.))))))>>>>>>>>>>>.....>>..>>>>..>>>>
>>>.........<<<<<<...<<.......>>...>>>>>>.........
......<<<<...<<<<..<.<<<<<<<......>>>>>>>...>.<<<.
........>>>.....>>>>.......>>>>......<<<<<<<....>>
>.>>>>........>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<..
...............>>>>>.><<<<<...<<<<....<<<<<<<<<<]]
..>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.........
..>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<...
...<<.......<<<....>>>....>>........<<<<.....<<<.<
<<<<.......>>>>>.>>>....>>>>..............>>>>>.>>
>>>...<<<<<<<.............>>....<<<<<<<<<.<<<....<
<<<....<<<<<......>>>>>...>>>>...>>>....>>>>..>>>>
>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv5 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		K17 V19 N21 S23 S49 A51 R52 F58 A67 H69 R95 N96 S98 E99 T100 N102 G104 F105 G106 I107 G125 D127 Y129 C131 R143 R148
Binding residue
(residue number reindexed from 1)		K13 V15 N17 S19 S45 A47 R48 F54 A63 H65 R91 N92 S94 E95 T96 N98 G100 F101 G102 I103 G121 D123 Y125 C127 R139 R144
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8pv5, PDBe:8pv5, PDBj:8pv5
PDBsum8pv5
PubMed37921038
UniProtG0SHQ2

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