Structure of PDB 5wlc Chain LJ Binding Site BS01

Receptor Information
>5wlc Chain LJ (length=493) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTHISFNPQH
PHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDA
TGLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRL
WDISNAYEPQLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSS
GSTPIYSLNHDQPVENVIAVSPTQIVSCGGNNFKVWDLTSNKKLYERGNF
NKAVTCLDYVENFDSPMQSALIASSLDGHVKVFDPLDNFQVKFGWKFSGP
VLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKKKSNNFQRMMRGSEYQGD
QEHIIHNDKVRSQRRMRAFERNINQFKWSEALDNAFVPGMAKELTLTVLQ
ELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRSASIVADWVAVVLEL
YGNTLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLT
Ligand information
>5wlc Chain L0 (length=488) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagacaagugcuugucguucguuaauggccucgucaaacgguggagaga
gucgcuaggugaucgucagaucugccuagucucuauacagcguguuuaau
ugacauggguugaugcguauugagagauacaauuugggaagaaauuccca
gaguguguuucuuuugcguuuaaccugaacagucucaucgugggcaucuu
gcgauuccauuggugagcagcgaaggauuugguggauuacuagcuaauag
caaucuauuucaaagaauucaaacuugggggaaugccuuguugaauauuc
uucaaguguaaccuccucucaaaucagcgauaucaaacguaccccgugaa
acaccgggguaucuguuugguggaaccugauuagaggaaacucaaagagu
gcuaugguauggugacggagugcgcuggucaagaguguaaaagcuuuuug
aacagagagcauuuccggcagcagagauuucagcuguu
<<<<<<<<<..>>>>>>.>>>............<<<<<<<<.<<...<<<
<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>...>>.>>>......>
>>>>..<<<<<<..<<<<<..<<<<<<<<<<.<<<<<<<<....>>>>>>
>>.>>>>>>>>>>.>>>>>.>>>>>>.......<<<<<<<<<<<......
.....>>>>>.>>>>>>.........................<<<...>>
>.........................<<<<<..<<<<<<<..<<<..>>>
..>>>>.>>.>>>>>>.....<<<<<<...<<<<<<<<<<<<<<<<....
....>>>>>>>.>.>>>>>>>>....>>>>>>..................
...............<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>
>.>>>...>>>>.>>>><<<<<.<<<..>>>.>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5wlc The complete structure of the small-subunit processome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R5 T20 P22 R25 R28 T31 P267 S354 N355 N356 F357 R359 M360 M361 K378 R380 S381 R386 F395 E412 D452 R454
Binding residue
(residue number reindexed from 1)		R4 T19 P21 R24 R27 T30 P266 S335 N336 N337 F338 R340 M341 M342 K359 R361 S362 R367 F376 E393 D433 R435
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0033553 rDNA heterochromatin
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum5wlc
PubMed28945246
UniProtQ04305|UTP15_YEAST U3 small nucleolar RNA-associated protein 15 (Gene Name=UTP15)

[Back to BioLiP]